gspt1 G1 to S phase transition 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gspt1provided by ZNC
Official Full Name: G1 to S phase transition 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040822-36
See related: Ensembl:ENSDARG00000031048 AllianceGenome:ZFIN:ZDB-GENE-040822-36
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:91975
Summary: Predicted to enable GTPase activity and translation release factor activity. Predicted to be involved in cytoplasmic translational termination. Predicted to be part of translation release factor complex. Is expressed in axial mesoderm; immature eye; myotome; optic primordium; and retina. Orthologous to several human genes including GSPT1 (G1 to S phase transition 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (19362379..19383945)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (19240505..19262071)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables translation release factor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in translation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of translation release factor complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: eukaryotic peptide chain release factor GTP-binding subunit ERF3A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003992.1 → NP_001003992.1 eukaryotic peptide chain release factor GTP-binding subunit ERF3A

See identical proteins and their annotated locations for NP_001003992.1

Status: PROVISIONAL

Source sequence(s)

BC080263

UniProtKB/TrEMBL

B2GQ36, Q68EH0

Related

ENSDARP00000041710.6, ENSDART00000041711.7

Conserved Domains (5) summary

cd01883
Location:141 → 358

EF1_alpha; Elongation Factor 1-alpha (EF1-alpha) protein family

COG5256
Location:138 → 561

TEF1; Translation elongation factor EF-1alpha (GTPase) [Translation, ribosomal structure and biogenesis]

pfam07145
Location:32 → 44

PAM2; Ataxin-2 C-terminal region

cd04089
Location:366 → 447

eRF3_II; Domain II of the eukaryotic class II release factor

cd03704
Location:453 → 559

eRF3_C_III; C-terminal domain of eRF3