U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

alg6 ALG6 alpha-1,3-glucosyltransferase [ Danio rerio (zebrafish) ]

Gene ID: 445327, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
alg6provided by ZNC
Official Full Name
ALG6 alpha-1,3-glucosyltransferaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040808-45
See related
Ensembl:ENSDARG00000017617 AllianceGenome:ZFIN:ZDB-GENE-040808-45
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:100813
Summary
Predicted to enable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ic. Orthologous to human ALG6 (ALG6 alpha-1,3-glucosyltransferase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See alg6 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (32065094..32087108, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (32078180..32100194, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene EF-hand calcium binding domain 7 Neighboring gene integrin subunit beta 3 binding protein Neighboring gene uncharacterized LOC137495977 Neighboring gene forkhead box D3

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A novel FoxD3 gene trap line reveals neural crest precursor movement and a role for FoxD3 in their specification. Hochgreb-Hägele T, et al. Dev Biol, 2013 Feb 1. PMID 23228892, Free PMC Article
  2. Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. Sreenivasan R, et al. PLoS One, 2008 Mar 12. PMID 18335061, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in dolichol-linked oligosaccharide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein N-linked glycosylation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
Names
asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)
asparagine-linked glycosylation 6 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase)
NP_001003784.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003784.2 → NP_001003784.2  dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase precursor

    Status: VALIDATED

    Source sequence(s)
    BC079496, EH486981, EH513372, EV563686
    UniProtKB/TrEMBL
    A0A8M1N1I1
    Related
    ENSDARP00000126123.1, ENSDART00000150934.3
    Conserved Domains (1) summary
    pfam03155
    Location:32 → 486
    Alg6_Alg8; ALG6, ALG8 glycosyltransferase family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    32065094..32087108 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools