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chrne - cholinergic receptor, nicotinic, epsilon

Contributes to acetylcholine receptor activity. Acts upstream of or within cellular response to acetylcholine and cholinergic synaptic transmission. Part of acetylcholine-gated channel complex. Is expressed in central nervous system; mesoderm; musculature system; and somite. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome; congenital myasthenic syndrome 4A; congenital myasthenic syndrome 4B; and congenital myasthenic syndrome 4C. Orthologous to human CHRNE (cholinergic receptor nicotinic epsilon subunit). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa