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cep57l1 centrosomal protein 57, like 1 [ Danio rerio (zebrafish) ]

Gene ID: 445312, updated on 12-Sep-2024

Summary

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Official Symbol
cep57l1provided by ZNC
Official Full Name
centrosomal protein 57, like 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040808-27
See related
Ensembl:ENSDARG00000002826 AllianceGenome:ZFIN:ZDB-GENE-040808-27
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:101037
Summary
Predicted to enable microtubule binding activity. Predicted to be located in cytoplasm. Predicted to be active in centrosome. Orthologous to human CEP57L1 (centrosomal protein 57 like 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See cep57l1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (32141562..32149034, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (32238687..32246151, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene glutamate receptor, metabotropic 1a Neighboring gene CD164 molecule, sialomucin Neighboring gene si:ch211-51a19.5 Neighboring gene sestrin 1 Neighboring gene armadillo repeat containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Phylogenetic, syntenic, and tissue expression analysis of slc22 genes in zebrafish (Danio rerio). Mihaljevic I, et al. BMC Genomics, 2016 Aug 12. PMID 27519738, Free PMC Article
  2. FOXO genes in channel catfish and their response after bacterial infection. Gao L, et al. Dev Comp Immunol, 2019 Aug. PMID 30905685
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables gamma-tubulin binding IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
  
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
centrosomal protein CEP57L1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003769.2 → NP_001003769.2  centrosomal protein CEP57L1

    Status: VALIDATED

    Source sequence(s)
    EH434685, EH460689, EH508654, EH534787
    UniProtKB/TrEMBL
    A0A8M1N1U1
    Related
    ENSDARP00000048536.4, ENSDART00000048537.6
    Conserved Domains (2) summary
    pfam06657
    Location:347 → 408
    Cep57_MT_bd; Centrosome microtubule-binding domain of Cep57
    pfam14073
    Location:68 → 244
    Cep57_CLD; Centrosome localization domain of Cep57

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    32141562..32149034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068215417.1 → XP_068071518.1  centrosomal protein CEP57L1 isoform X3

  2. XM_068215416.1 → XP_068071517.1  centrosomal protein CEP57L1 isoform X2

  3. XM_005160678.5 → XP_005160735.1  centrosomal protein CEP57L1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B7K9
    Conserved Domains (2) summary
    pfam06657
    Location:348 → 409
    Cep57_MT_bd; Centrosome microtubule-binding domain of Cep57
    pfam14073
    Location:69 → 245
    Cep57_CLD; Centrosome localization domain of Cep57
Nucleotide Protein Strain
Heading Accession and Version

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