kptn kaptin (actin binding protein) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: kptnprovided by ZNC
Official Full Name: kaptin (actin binding protein)provided by ZNC
Primary source: ZFIN:ZDB-GENE-040801-258
See related: Ensembl:ENSDARG00000015937 AllianceGenome:ZFIN:ZDB-GENE-040801-258
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fc13b08; wu:fc13b09; zgc:100793
Summary: Predicted to enable actin filament binding activity. Predicted to be involved in cellular response to amino acid starvation and negative regulation of TORC1 signaling. Predicted to act upstream of or within actin filament organization. Predicted to be located in actin cytoskeleton. Predicted to be part of KICSTOR complex. Predicted to be active in lamellipodium. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 41. Orthologous to human KPTN (kaptin, actin binding protein). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (36913765..36924505, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (36313612..36324352, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fc13b08.x1 (e-PCR)
- UniSTS:192614

fc13b08.x1 (e-PCR)
- UniSTS:192615

fc13b09.x1 (e-PCR)
- UniSTS:192616

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info
enables actin filament binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within actin filament organization	IEA Inferred from Electronic Annotation more info
involved_in cellular response to amino acid starvation	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of TORC1 signaling	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of KICSTOR complex	IBA Inferred from Biological aspect of Ancestor more info
located_in actin cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in lamellipodium	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: KICSTOR complex protein kaptin

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.