polr2eb RNA polymerase II, I and III subunit E, b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: polr2ebprovided by ZNC
Official Full Name: RNA polymerase II, I and III subunit E, bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040801-83
See related: Ensembl:ENSDARG00000026183 AllianceGenome:ZFIN:ZDB-GENE-040801-83
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: polr2e; fk97g10; wu:fk97g10; zgc:101098
Summary: Predicted to enable DNA binding activity and DNA-directed 5'-3' RNA polymerase activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase II; and transcription elongation by RNA polymerase I. Predicted to act upstream of or within DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Orthologous to human POLR2E (RNA polymerase II, I and III subunit E). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 22

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (17606885..17611578)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (17581907..17586600)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-directed 5'-3' RNA polymerase activity	IEA Inferred from Electronic Annotation more info
contributes_to RNA polymerase I activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to RNA polymerase II activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to RNA polymerase III activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in tRNA transcription by RNA polymerase III	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription elongation by RNA polymerase I	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of DNA-directed RNA polymerase complex	IEA Inferred from Electronic Annotation more info
part_of RNA polymerase I complex	IBA Inferred from Biological aspect of Ancestor more info
part_of RNA polymerase II, core complex	IBA Inferred from Biological aspect of Ancestor more info
part_of RNA polymerase III complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: DNA-directed RNA polymerases I, II, and III subunit RPABC1

Names: polymerase (RNA) II (DNA directed) polypeptide E, b

NP_001003564.1

EC 2.7.7.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003564.2 → NP_001003564.1 DNA-directed RNA polymerases I, II, and III subunit RPABC1

See identical proteins and their annotated locations for NP_001003564.1

Status: PROVISIONAL

Source sequence(s)

BC077151

UniProtKB/TrEMBL

A0A8M1N1N6, Q6DEG5

Related

ENSDARP00000028718.6, ENSDART00000035670.7

Conserved Domains (3) summary

PLN03111
Location:1 → 209

PLN03111; DNA-directed RNA polymerase II subunit family protein; Provisional

pfam01191
Location:138 → 209

RNA_pol_Rpb5_C; RNA polymerase Rpb5, C-terminal domain

pfam03871
Location:4 → 92

RNA_pol_Rpb5_N; RNA polymerase Rpb5, N-terminal domain