ube2e2 ubiquitin-conjugating enzyme E2E 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ube2e2provided by ZNC
Official Full Name: ubiquitin-conjugating enzyme E2E 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-040801-237
See related: Ensembl:ENSDARG00000034670 AllianceGenome:ZFIN:ZDB-GENE-040801-237
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92467; wu:fb38h07
Summary: Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein K48-linked ubiquitination. Predicted to be active in nucleus. Is expressed in brain; margin; midbrain hindbrain boundary; segmental plate; and tail bud. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human UBE2E2 (ubiquitin conjugating enzyme E2 E2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 16

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (50007000..50076303)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (49797131..49866654)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fb38h07 (e-PCR)
- UniSTS:187168

G39769 (e-PCR)
- UniSTS:22228

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables ubiquitin conjugating enzyme activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin conjugating enzyme activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein K48-linked ubiquitination	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ubiquitin-conjugating enzyme E2 E2

NP_001003494.1

EC 6.3.2.19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.