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rhpn2.S rhophilin, Rho GTPase binding protein 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444802, updated on 4-Nov-2024

Summary

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Official Symbol
rhpn2.S
Official Full Name
rhophilin, Rho GTPase binding protein 2 S homeolog
Primary source
Xenbase:XB-GENE-17330332
Locus tag
XELAEV_18001948mg
See related
EnsemblRapid:ENSXLAG00005017915 AllianceGenome:Xenbase:XB-GENE-17330332
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
rhpn2-A
Summary
Predicted to act upstream of or within negative regulation of stress fiber assembly and signal transduction. Predicted to be located in perinuclear region of cytoplasm. Orthologous to human RHPN2 (rhophilin Rho GTPase binding protein 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rhpn2.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (50821504..50865747)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694816.1 (3821098..3865334)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene LDL receptor related protein 3 S homeolog Neighboring gene transfer RNA threonine (anticodon AGU) Neighboring gene E3 ubiquitin-protein ligase RNF182 Neighboring gene solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC82140

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of stress fiber assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
rhophilin-2-A
Names
GTP-Rho-binding protein 2-A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092904.1 → NP_001086373.1  rhophilin-2-A

    See identical proteins and their annotated locations for NP_001086373.1

    Status: PROVISIONAL

    Source sequence(s)
    BC075182
    UniProtKB/Swiss-Prot
    Q6DJJ6
    UniProtKB/TrEMBL
    A0A974D5K9
    Related
    ENSXLAP00005052883.1, ENSXLAT00005054055.1
    Conserved Domains (3) summary
    cd09249
    Location:111 → 495
    BRO1_Rhophilin_2; Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin-2
    cd00992
    Location:513 → 590
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl00087
    Location:26 → 107
    HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    50821504..50865747
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6DJJ6.1 GenPept UniProtKB/Swiss-Prot:Q6DJJ6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials