U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

arl2bp.L ARF like GTPase 2 binding protein L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444754, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
arl2bp.L
Official Full Name
ARF like GTPase 2 binding protein L homeolog
Primary source
Xenbase:XB-GENE-6254371
Locus tag
XELAEV_18022520mg
See related
EnsemblRapid:ENSXLAG00005017634 AllianceGenome:Xenbase:XB-GENE-6254371
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
arl2bp
Summary
Predicted to act upstream of or within maintenance of protein location in nucleus and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to be located in several cellular components, including cilium; microtubule cytoskeleton; and mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in retinitis pigmentosa with or without situs inversus. Orthologous to human ARL2BP (ADP ribosylation factor like GTPase 2 binding protein). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See arl2bp.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (43580677..43591274)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (41065747..41110527)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7L NC_030736.1 (111313319..111331109, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene spalt-like transcription factor 1 L homeolog Neighboring gene CYLD lysine 63 deubiquitinase L homeolog Neighboring gene ring finger and SPRY domain containing 1 L homeolog Neighboring gene uncharacterized LOC121403008

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC81575, MGC84796, MGC130948

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within maintenance of protein location in nucleus IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of tyrosine phosphorylation of STAT protein IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in cilium IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial intermembrane space IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in organelle IEA
Inferred from Electronic Annotation
more info
  
located_in spindle IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ADP-ribosylation factor-like protein 2-binding protein
Names
ADP ribosylation factor like GTPase 2 binding protein L homeolog
ADP-ribosylation factor-like 2 binding protein
ARF-like 2-binding protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092856.2 → NP_001086325.1  ADP-ribosylation factor-like protein 2-binding protein

    See identical proteins and their annotated locations for NP_001086325.1

    Status: VALIDATED

    Source sequence(s)
    BC077374
    UniProtKB/Swiss-Prot
    Q6DDX7, Q6GLJ7
    Related
    ENSXLAP00005052017.1, ENSXLAT00005053181.1
    Conserved Domains (1) summary
    pfam11527
    Location:25 → 132
    ARL2_Bind_BART; The ARF-like 2 binding protein BART

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    43580677..43591274
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041589321.1 → XP_041445255.1  ADP-ribosylation factor-like protein 2-binding protein isoform X1

    UniProtKB/TrEMBL
    A0A1L8GKJ3, A0A974D3G1
    Conserved Domains (1) summary
    pfam11527
    Location:22 → 132
    ARL2_Bind_BART; The ARF-like 2 binding protein BART
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6DDX7.1 GenPept UniProtKB/Swiss-Prot:Q6DDX7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.