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stx3.L syntaxin 3 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444751, updated on 4-Nov-2024

Summary

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Official Symbol
stx3.L
Official Full Name
syntaxin 3 L homeolog
Primary source
Xenbase:XB-GENE-5825388
Locus tag
XELAEV_18000056mg
See related
EnsemblRapid:ENSXLAG00005031096 AllianceGenome:Xenbase:XB-GENE-5825388
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
stx3
Summary
Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to act upstream of or within exocytosis; intracellular protein transport; and vesicle docking. Predicted to be located in postsynapse; presynaptic active zone membrane; and synaptic vesicle. Predicted to be part of SNARE complex. Human ortholog(s) of this gene implicated in congenital diarrhea. Orthologous to human STX3 (syntaxin 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See stx3.L in Genome Data Viewer
Location:
chromosome: 7L
Exon count:
13
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7L NC_054383.1 (64256576..64285148, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694896.1 (279201..307840)

Chromosome 7L - NC_054383.1Genomic Context describing neighboring genes Neighboring gene glycine N-acyltransferase-like Neighboring gene cobalamin binding intrinsic factor Neighboring gene pre-mRNA processing factor 19 L homeolog Neighboring gene transmembrane protein 132A L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC84264, MGC84790

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables SNAP receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables SNARE binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within exocytic insertion of neurotransmitter receptor to postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within synaptic vesicle fusion to presynaptic active zone membrane IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vesicle docking IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SNARE complex IEA
Inferred from Electronic Annotation
more info
  
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in postsynapse IEA
Inferred from Electronic Annotation
more info
  
located_in presynaptic active zone membrane IEA
Inferred from Electronic Annotation
more info
  
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
syntaxin 3 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092853.1 → NP_001086322.1  syntaxin 3 L homeolog

    See identical proteins and their annotated locations for NP_001086322.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082457
    UniProtKB/TrEMBL
    A0A8J0PW29, A0A974GZE5, A0AA97PZ73, Q6GLJ9
    Conserved Domains (3) summary
    cd00179
    Location:30 → 179
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
    pfam00804
    Location:30 → 225
    Syntaxin; Syntaxin
    cl22856
    Location:189 → 257
    SNARE; SNARE motif

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    64256576..64285148 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041568499.1 → XP_041424433.1  syntaxin 3 L homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J1L4I2
    Related
    ENSXLAP00005093187.1, ENSXLAT00005094869.1
    Conserved Domains (2) summary
    cd00179
    Location:30 → 179
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
    cl22856
    Location:189 → 257
    SNARE; SNARE motif

  2. XM_041568496.1 → XP_041424430.1  syntaxin 3 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1L657
    Conserved Domains (2) summary
    cd00179
    Location:30 → 179
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
    cd15881
    Location:189 → 257
    SNARE_syntaxin3; SNARE motif of syntaxin 3

  3. XM_041568495.1 → XP_041424429.1  syntaxin 3 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1L657
    Conserved Domains (2) summary
    cd00179
    Location:30 → 179
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
    cd15881
    Location:189 → 257
    SNARE_syntaxin3; SNARE motif of syntaxin 3

  4. XM_041568497.1 → XP_041424431.1  syntaxin 3 L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1L4G0
    Related
    ENSXLAP00005093255.1, ENSXLAT00005094938.1
    Conserved Domains (2) summary
    cd00179
    Location:30 → 179
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
    cl22856
    Location:189 → 257
    SNARE; SNARE motif

  5. XM_041568494.1 → XP_041424428.1  syntaxin 3 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1L4H7
    Related
    ENSXLAP00005093370.1, ENSXLAT00005095053.1
    Conserved Domains (2) summary
    cd00179
    Location:30 → 179
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
    cl22856
    Location:189 → 257
    SNARE; SNARE motif

  6. XM_018242278.2 → XP_018097767.1  syntaxin 3 L homeolog isoform X6

    UniProtKB/TrEMBL
    A0A8J0U6V1, A0A974CBU8
    Related
    ENSXLAP00005093441.1, ENSXLAT00005095125.1

  7. XM_018242277.2 → XP_018097766.1  syntaxin 3 L homeolog isoform X4

    UniProtKB/TrEMBL
    A0A310U8E8, A0A974CBU8, A0A974GZE1, A0AA97PYK9
    Related
    ENSXLAP00005093115.1, ENSXLAT00005094799.1
Nucleotide Protein Strain
Heading Accession and Version

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