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acsf3.S acyl-CoA synthetase family member 3 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444743, updated on 4-Nov-2024

Summary

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Official Symbol
acsf3.S
Official Full Name
acyl-CoA synthetase family member 3 S homeolog
Primary source
Xenbase:XB-GENE-964816
Locus tag
XELAEV_18024864mg
See related
EnsemblRapid:ENSXLAG00005009258 AllianceGenome:Xenbase:XB-GENE-964816
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
acsf3
Summary
Predicted to enable ATP binding activity; malonyl-CoA synthetase activity; and medium-chain fatty acid-CoA ligase activity. Predicted to act upstream of or within fatty acid metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined malonic and methylmalonic acidemia. Orthologous to human ACSF3 (acyl-CoA synthetase family member 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See acsf3.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (40475190..40502575)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (39365197..39391754)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108715406 Neighboring gene CBFA2/RUNX1 translocation partner 3 S homeolog Neighboring gene cadherin 15 S homeolog Neighboring gene cyclin-O protein B-like Neighboring gene cadherin-15-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC84772

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables malonyl-CoA synthetase activity IEA
Inferred from Electronic Annotation
more info
  
enables medium-chain fatty acid-CoA ligase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
malonate--CoA ligase ACSF3, mitochondrial
Names
acyl-CoA synthetase family member 3, mitochondrial
NP_001086314.2
XP_018115096.1
XP_018115099.1
XP_018115100.1
XP_041447257.1
XP_041447258.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092845.1 → NP_001086314.2  malonate--CoA ligase ACSF3, mitochondrial

    Status: PROVISIONAL

    Source sequence(s)
    BC074473
    UniProtKB/Swiss-Prot
    Q6GLK6
    Related
    ENSXLAP00005026975.1, ENSXLAT00005027707.1
    Conserved Domains (1) summary
    cd05941
    Location:67 → 583
    MCS; Malonyl-CoA synthetase (MCS)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    40475190..40502575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018259610.2 → XP_018115099.1  malonate--CoA ligase ACSF3, mitochondrial isoform X1

    UniProtKB/Swiss-Prot
    Q6GLK6
    UniProtKB/TrEMBL
    A0A1L8GEQ0, A0A974HLM5
    Conserved Domains (1) summary
    cd05941
    Location:67 → 583
    MCS; Malonyl-CoA synthetase (MCS)

  2. XM_018259607.2 → XP_018115096.1  malonate--CoA ligase ACSF3, mitochondrial isoform X1

    UniProtKB/Swiss-Prot
    Q6GLK6
    UniProtKB/TrEMBL
    A0A1L8GEQ0, A0A974HLM5
    Conserved Domains (1) summary
    cd05941
    Location:67 → 583
    MCS; Malonyl-CoA synthetase (MCS)

  3. XM_041591323.1 → XP_041447257.1  malonate--CoA ligase ACSF3, mitochondrial isoform X1

    UniProtKB/Swiss-Prot
    Q6GLK6
    UniProtKB/TrEMBL
    A0A1L8GEQ0, A0A974HLM5
    Conserved Domains (1) summary
    cd05941
    Location:67 → 583
    MCS; Malonyl-CoA synthetase (MCS)

  4. XM_041591324.1 → XP_041447258.1  malonate--CoA ligase ACSF3, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8J1N1C7
    Conserved Domains (1) summary
    cd05941
    Location:1 → 315
    MCS; Malonyl-CoA synthetase (MCS)

  5. XM_018259611.2 → XP_018115100.1  malonate--CoA ligase ACSF3, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8J1N1C7
    Conserved Domains (1) summary
    cd05941
    Location:1 → 315
    MCS; Malonyl-CoA synthetase (MCS)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6GLK6.1 GenPept UniProtKB/Swiss-Prot:Q6GLK6

Gene LinkOut

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