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desi1.L desumoylating isopeptidase 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444727, updated on 4-Nov-2024

Summary

Official Symbol
desi1.L
Official Full Name
desumoylating isopeptidase 1 L homeolog
Primary source
Xenbase:XB-GENE-998986
Locus tag
XELAEV_18023499mg
See related
EnsemblRapid:ENSXLAG00005013224 AllianceGenome:Xenbase:XB-GENE-998986
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
desi1; DeSI-1; pppde2; fam152b
Summary
Predicted to enable long-chain fatty acyl-CoA hydrolase activity. Predicted to act upstream of or within protein modification by small protein removal and proteolysis. Predicted to be located in cytoplasm and nucleus. Orthologous to human DESI1 (desumoylating isopeptidase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See desi1.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (110912033..110925946)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (105660208..105674251)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein 13 L homeolog Neighboring gene X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog Neighboring gene phosphomannomutase 2 L homeolog Neighboring gene cold shock domain containing C2 L homeolog

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC84710

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables long-chain fatty acyl-CoA hydrolase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables palmitoyl-(protein) hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within protein modification by small protein removal IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
desumoylating isopeptidase 1
Names
PPPDE peptidase domain containing 2
PPPDE peptidase domain-containing protein 2
S-depalmitoylase DESI1
palmitoyl protein thioesterase DESI1
NP_001086298.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092829.1NP_001086298.1  desumoylating isopeptidase 1

    See identical proteins and their annotated locations for NP_001086298.1

    Status: PROVISIONAL

    Source sequence(s)
    BC074444
    UniProtKB/Swiss-Prot
    Q6GLM5
    UniProtKB/TrEMBL
    A0A974D554
    Related
    ENSXLAP00005039033.1, ENSXLAT00005039954.1
    Conserved Domains (1) summary
    pfam05903
    Location:8150
    Peptidase_C97; PPPDE putative peptidase domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    110912033..110925946
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)