spock2.S SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: spock2.S
Official Full Name: SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 S homeolog
Primary source: Xenbase:XB-GENE-1003770
Locus tag: XELAEV_18037101mg
See related: EnsemblRapid:ENSXLAG00005004910
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: spock2
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Genomic context

Location:: chromosome: 7S

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7S	NC_054384.1 (30219800..30309032)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7S	NC_030737.1 (28706638..28796638)

Chromosome 7S - NC_054384.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables collagen binding	IEA Inferred from Electronic Annotation more info
enables extracellular matrix binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in extracellular space	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 S homeolog

Names: sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001092823.1 → NP_001086292.1 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 S homeolog precursor

See identical proteins and their annotated locations for NP_001086292.1

Status: PROVISIONAL

Source sequence(s)

BC074435

UniProtKB/TrEMBL

A0A974CBE8, Q6GLM8

Related

ENSXLAP00005014705.1, ENSXLAT00005014901.1

Conserved Domains (4) summary

cd00191
Location:310 → 374

TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases

cd00252
Location:196 → 311

SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...

pfam07648
Location:135 → 176

Kazal_2; Kazal-type serine protease inhibitor domain

pfam10591
Location:195 → 301

SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region