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rasgef1a.L RasGEF domain family member 1A L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444680, updated on 18-Sep-2024

Summary

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Official Symbol
rasgef1a.L
Official Full Name
RasGEF domain family member 1A L homeolog
Primary source
Xenbase:XB-GENE-5739378
Locus tag
XELAEV_18034970mg
See related
EnsemblRapid:ENSXLAG00005028828
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
rasgef1a
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Genomic context

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See rasgef1a.L in Genome Data Viewer
Location:
chromosome: 7L
Exon count:
17
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7L NC_054383.1 (48919267..49070918, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7L NC_030736.1 (46421718..46454699, complement)

Chromosome 7L - NC_054383.1Genomic Context describing neighboring genes Neighboring gene ret proto-oncogene L homeolog Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 2 L homeolog Neighboring gene pulmonary surfactant-associated protein D Neighboring gene surfactant, pulmonary-associated protein A L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC84301

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RasGEF domain family member 1A L homeolog; rasGEF domain family member 1A L homeolog
Names
RasGEF domain family, member 1A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092782.1 → NP_001086251.1  RasGEF domain family member 1A L homeolog

    See identical proteins and their annotated locations for NP_001086251.1

    Status: PROVISIONAL

    Source sequence(s)
    BC074379
    UniProtKB/TrEMBL
    A0A974CFV4, Q6GLS6
    Related
    ENSXLAP00005086021.1, ENSXLAT00005087683.1
    Conserved Domains (2) summary
    cd06224
    Location:4 → 102
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    cl02485
    Location:152 → 399
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    48919267..49070918 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041568487.1 → XP_041424421.1  rasGEF domain family member 1A L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1L4E9, A0A974CFV4
    Conserved Domains (2) summary
    cd06224
    Location:41 → 158
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:212 → 404
    RasGEF; RasGEF domain

  2. XM_041568486.1 → XP_041424420.1  rasGEF domain family member 1A L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1L752, A0A974CFV4
    Related
    ENSXLAP00005086344.1, ENSXLAT00005088006.1
    Conserved Domains (2) summary
    cd06224
    Location:51 → 168
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    cl02485
    Location:218 → 465
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  3. XM_018224493.2 → XP_018079982.1  rasGEF domain family member 1A L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8FK65, A0A974CFV4, A0A974HBP6
    Related
    ENSXLAP00005086088.1, ENSXLAT00005087750.1

  4. XM_018224494.2 → XP_018079983.1  rasGEF domain family member 1A L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1L4E9, A0A974CFV4
    Conserved Domains (2) summary
    cd06224
    Location:41 → 158
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:212 → 404
    RasGEF; RasGEF domain
Nucleotide Protein Strain
Heading Accession and Version

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