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tlcd4.2.L TLC domain containing 4, gene 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444633, updated on 4-Nov-2024

Summary

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Official Symbol
tlcd4.2.L
Official Full Name
TLC domain containing 4, gene 2 L homeolog
Primary source
Xenbase:XB-GENE-6254610
Locus tag
XELAEV_18004447mg
See related
EnsemblRapid:ENSXLAG00005002533 AllianceGenome:Xenbase:XB-GENE-6254610
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tlcd4-a; tmem56-a; tmem56.2; tmem56.2.L
Summary
Predicted to act upstream of or within lipid homeostasis. Predicted to be located in endoplasmic reticulum and membrane. Orthologous to human TLCD4 (TLC domain containing 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tlcd4.2.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (148866438..148891898)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694872.1 (464456..488061)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene ELAV like neuron-specific RNA binding protein 3 L homeolog Neighboring gene zinc finger protein 653 L homeolog Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC121401633 Neighboring gene calponin L homeolog Neighboring gene uncharacterized LOC121401632

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC84146

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within lipid homeostasis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
TLC domain-containing protein 4-A
Names
transmembrane protein 56 L homeolog
transmembrane protein 56-A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092735.1 → NP_001086204.1  TLC domain-containing protein 4-A

    See identical proteins and their annotated locations for NP_001086204.1

    Status: PROVISIONAL

    Source sequence(s)
    BC074322
    UniProtKB/Swiss-Prot
    Q6GLX2
    UniProtKB/TrEMBL
    A0A310U3T9, A0A974GZQ0, A0AA97PZ03
    Related
    ENSXLAP00005007542.1, ENSXLAT00005007660.1
    Conserved Domains (1) summary
    pfam03798
    Location:47 → 238
    TRAM_LAG1_CLN8; TLC domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    148866438..148891898
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041585098.1 → XP_041441032.1  TLC domain-containing protein 4-A isoform X1

    UniProtKB/Swiss-Prot
    Q6GLX2
    UniProtKB/TrEMBL
    A0A310U3T9, A0A974GZQ0, A0AA97PZ03
    Conserved Domains (1) summary
    pfam03798
    Location:47 → 238
    TRAM_LAG1_CLN8; TLC domain

  2. XM_018242023.2 → XP_018097512.1  TLC domain-containing protein 4-A isoform X1

    UniProtKB/Swiss-Prot
    Q6GLX2
    UniProtKB/TrEMBL
    A0A310U3T9, A0A974GZQ0, A0AA97PZ03
    Conserved Domains (1) summary
    pfam03798
    Location:47 → 238
    TRAM_LAG1_CLN8; TLC domain

  3. XM_018242024.2 → XP_018097513.1  TLC domain-containing protein 4-A isoform X1

    UniProtKB/Swiss-Prot
    Q6GLX2
    UniProtKB/TrEMBL
    A0A310U3T9, A0A974GZQ0, A0AA97PZ03
    Conserved Domains (1) summary
    pfam03798
    Location:47 → 238
    TRAM_LAG1_CLN8; TLC domain

  4. XM_041585097.1 → XP_041441031.1  TLC domain-containing protein 4-A isoform X1

    UniProtKB/Swiss-Prot
    Q6GLX2
    UniProtKB/TrEMBL
    A0A310U3T9, A0A974GZQ0, A0AA97PZ03
    Conserved Domains (1) summary
    pfam03798
    Location:47 → 238
    TRAM_LAG1_CLN8; TLC domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6GLX2.1 GenPept UniProtKB/Swiss-Prot:Q6GLX2

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