rdh5.L retinol dehydrogenase 5 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: rdh5.L
Official Full Name: retinol dehydrogenase 5 L homeolog
Primary source: Xenbase:XB-GENE-1011662
Locus tag: XELAEV_18013343mg
See related: EnsemblRapid:ENSXLAG00005007345 AllianceGenome:Xenbase:XB-GENE-1011662
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: rdh5
Summary: Predicted to enable all-trans-retinol dehydrogenase (NAD+) activity. Predicted to act upstream of or within retinoid metabolic process and steroid metabolic process. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in fundus albipunctatus and night blindness. Orthologous to human RDH5 (retinol dehydrogenase 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 2L

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2L	NC_054373.1 (143860108..143871386)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2L	NC_030726.1 (137976930..137988277)

Chromosome 2L - NC_054373.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables all-trans-retinol dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within retinoid metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within steroid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in intracellular membrane-bounded organelle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: retinol dehydrogenase 5 L homeolog

Names: retinol dehydrogenase 5 (11-cis/9-cis) L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001092725.1 → NP_001086194.1 retinol dehydrogenase 5 L homeolog precursor

See identical proteins and their annotated locations for NP_001086194.1

Status: PROVISIONAL

Source sequence(s)

BC074312

UniProtKB/TrEMBL

A0A974HZJ2, Q6GLY2

Related

ENSXLAP00005020986.1, ENSXLAT00005021608.1

Conserved Domains (2) summary

cd09805
Location:30 → 307

type2_17beta_HSD-like_SDR_c; human 17beta-hydroxysteroid dehydrogenase type 2 (type 2 17beta-HSD)-like, classical (c) SDRs

pfam00106
Location:30 → 214

adh_short; short chain dehydrogenase