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otud6b.L OTU deubiquitinase 6B L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444600, updated on 4-Nov-2024

Summary

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Official Symbol
otud6b.L
Official Full Name
OTU deubiquitinase 6B L homeolog
Primary source
Xenbase:XB-GENE-17335325
Locus tag
XELAEV_18032180mg
See related
EnsemblRapid:ENSXLAG00005026509 AllianceGenome:Xenbase:XB-GENE-17335325
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
duba5; epid35; otud6b
Summary
Predicted to enable cysteine-type deubiquitinase activity. Predicted to act upstream of or within protein deubiquitination. Is expressed in dermal system and ectoderm. Orthologous to human OTUD6B (OTU deubiquitinase 6B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See otud6b.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (136443680..136450544)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (127276353..127288781)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene chromosome 6 C8orf88 homolog L homeolog Neighboring gene phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 L homeolog Neighboring gene leucine rich repeat containing 69 L homeolog Neighboring gene solute carrier family 26 (anion exchanger), member 7 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC84071

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
  
enables cysteine-type deubiquitinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein deubiquitination IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein deubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
deubiquitinase OTUD6B
Names
OTU domain containing 6B L homeolog
OTU domain-containing protein 6B
NP_001086171.1
XP_018121989.1
XP_041421382.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092702.1 → NP_001086171.1  deubiquitinase OTUD6B

    See identical proteins and their annotated locations for NP_001086171.1

    Status: PROVISIONAL

    Source sequence(s)
    BC074286
    UniProtKB/Swiss-Prot
    Q6GM06
    UniProtKB/TrEMBL
    A0A974CRA7
    Related
    ENSXLAP00005078811.1, ENSXLAT00005080402.1
    Conserved Domains (2) summary
    COG5539
    Location:4 → 285
    COG5539; Predicted cysteine protease (OTU family) [Posttranslational modification, protein turnover, chaperones]
    pfam02338
    Location:156 → 281
    OTU; OTU-like cysteine protease

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    136443680..136450544
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018266500.2 → XP_018121989.1  deubiquitinase OTUD6B isoform X1

    UniProtKB/TrEMBL
    A0A8J0VHL0, A0A974CRA7
    Related
    ENSXLAP00005078859.1, ENSXLAT00005080451.1

  2. XM_041565448.1 → XP_041421382.1  deubiquitinase OTUD6B isoform X2

    UniProtKB/TrEMBL
    A0A8J1KVQ2, A0A974CRA7
    Related
    ENSXLAP00005078921.1, ENSXLAT00005080512.1
    Conserved Domains (1) summary
    COG5539
    Location:14 → 255
    COG5539; Predicted cysteine protease (OTU family) [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6GM06.1 GenPept UniProtKB/Swiss-Prot:Q6GM06

Gene LinkOut

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