rflna.L refilin A L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Symbol: rflna.L
Full Name: refilin A L homeolog
Primary source: Xenbase:XB-GENE-986504
See related: EnsemblRapid:ENSXLAG00005009130 AllianceGenome:Xenbase:XB-GENE-986504
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: fam101a; fam101a.L
Summary: Predicted to enable filamin binding activity. Predicted to act upstream of or within several processes, including actin filament bundle organization; negative regulation of bone mineralization involved in bone maturation; and negative regulation of chondrocyte development. Predicted to be located in actin filament bundle and cytoplasm. Orthologous to human RFLNA (refilin A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 1S

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (149243805..149301444, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (133496179..133535458, complement)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables filamin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within actin filament bundle organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of bone mineralization involved in bone maturation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of chondrocyte development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of chondrocyte development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within skeletal system morphogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in actin filament bundle	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: refilin A L homeolog

Names: family with sequence similarity 101 member A L homeolog; family with sequence similarity 101, member A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001092695.1 → NP_001086164.1 refilin A L homeolog

See identical proteins and their annotated locations for NP_001086164.1

Status: PROVISIONAL

Source sequence(s)

BC074278

UniProtKB/TrEMBL

Q6GM13

Related

ENSXLAP00005026575.1, ENSXLAT00005027307.1

Conserved Domains (1) summary

pfam15068
Location:1 → 207

FAM101; FAM101 family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

149243805..149301444 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041575423.1 → XP_041431357.1 refilin A L homeolog isoform X1

UniProtKB/TrEMBL

Q6GM13

Conserved Domains (1) summary

pfam15068
Location:1 → 207

FAM101; FAM101 family