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ggh.L gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444589, updated on 4-Nov-2024

Summary

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Official Symbol
ggh.L
Official Full Name
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) L homeolog
Primary source
Xenbase:XB-GENE-944420
Locus tag
XELAEV_18032062mg
See related
EnsemblRapid:ENSXLAG00005015796 AllianceGenome:Xenbase:XB-GENE-944420
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ggh
Summary
Predicted to enable gamma-glutamyl-peptidase activity. Predicted to act upstream of or within glutamine metabolic process and tetrahydrofolylpolyglutamate metabolic process. Predicted to be located in extracellular region and vacuole. Orthologous to human GGH (gamma-glutamyl hydrolase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ggh.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (125911066..125930775, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (118779275..118799075, complement)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene Sodium/potassium transporting ATPase interacting 3 L homeolog Neighboring gene uncharacterized LOC121394731 Neighboring gene minichromosome maintenance domain containing 2 L homeolog Neighboring gene tocopherol (alpha) transfer protein L homeolog Neighboring gene YTH N6-methyladenosine RNA binding protein F3 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC84044

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables gamma-glutamyl-peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables omega peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tetrahydrofolylpolyglutamate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in vacuole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) L homeolog
NP_001086160.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092691.1 → NP_001086160.1  gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) L homeolog precursor

    See identical proteins and their annotated locations for NP_001086160.1

    Status: PROVISIONAL

    Source sequence(s)
    BC074274
    UniProtKB/TrEMBL
    A0A974CNN7, Q6GM17
    Related
    ENSXLAP00005046428.1, ENSXLAT00005047532.1
    Conserved Domains (2) summary
    cd01747
    Location:34 → 304
    GATase1_Glutamyl_Hydrolase; Type 1 glutamine amidotransferase (GATase1) domain found in gamma-Glutamyl Hydrolase
    pfam07722
    Location:32 → 244
    Peptidase_C26; Peptidase C26

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    125911066..125930775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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