lrwd1.L leucine-rich repeats and WD repeat domain containing 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: lrwd1.L
Official Full Name: leucine-rich repeats and WD repeat domain containing 1 L homeolog
Primary source: Xenbase:XB-GENE-959485
Locus tag: XELAEV_18011891mg
See related: EnsemblRapid:ENSXLAG00005013748
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ORCA; lrwd1
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 2L

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2L	NC_054373.1 (46901753..46919025, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2L	NC_030726.1 (45339546..45356818, complement)

Chromosome 2L - NC_054373.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables chromatin binding	ISS Inferred from Sequence or Structural Similarity more info
enables methyl-CpG binding	ISS Inferred from Sequence or Structural Similarity more info
enables methylated histone binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA replication	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chromatin organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chromatin organization	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within establishment of protein localization to chromatin	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in chromosome, centromeric region	IEA Inferred from Electronic Annotation more info
located_in chromosome, telomeric region	IEA Inferred from Electronic Annotation more info
located_in chromosome, telomeric region	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in kinetochore	IEA Inferred from Electronic Annotation more info
located_in kinetochore	ISS Inferred from Sequence or Structural Similarity more info
part_of nuclear origin of replication recognition complex	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
part_of pericentric heterochromatin	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: leucine-rich repeat and WD repeat-containing protein 1

Names: ORC-associated protein; origin recognition complex-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001092646.1 → NP_001086115.1 leucine-rich repeat and WD repeat-containing protein 1

See identical proteins and their annotated locations for NP_001086115.1

Status: PROVISIONAL

Source sequence(s)

BC074207

UniProtKB/Swiss-Prot

Q6GM71

UniProtKB/TrEMBL

A0A974DLQ0

Related

ENSXLAP00005040607.1, ENSXLAT00005041530.1

Conserved Domains (7) summary

COG2319
Location:429 → 722

WD40; WD40 repeat [General function prediction only]

cd00116
Location:10 → 127

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

sd00033
Location:23 → 48

LRR_RI; leucine-rich repeat [structural motif]

pfam12799
Location:48 → 89

LRR_4; Leucine Rich repeats (2 copies)

pfam13855
Location:27 → 81

LRR_8; Leucine rich repeat

sd00039
Location:362 → 403

7WD40; WD40 repeat [structural motif]

cl02567
Location:363 → 720

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

46901753..46919025 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)