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pan2.S poly(A) specific ribonuclease subunit PAN2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444430, updated on 4-Nov-2024

Summary

Official Symbol
pan2.S
Official Full Name
poly(A) specific ribonuclease subunit PAN2 S homeolog
Primary source
Xenbase:XB-GENE-985224
Locus tag
XELAEV_18015878mg
See related
AllianceGenome:Xenbase:XB-GENE-985224
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
pan2
Summary
Predicted to enable poly(A)-specific ribonuclease activity. Predicted to act upstream of or within nuclear-transcribed mRNA poly(A) tail shortening. Predicted to be located in P-body. Predicted to be part of PAN complex. Orthologous to human PAN2 (poly(A) specific ribonuclease subunit PAN2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See pan2.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (129664331..129679634)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (120659370..120674720)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121400680 Neighboring gene protein kinase C delta type-like Neighboring gene growth/differentiation factor 11 Neighboring gene uncharacterized LOC121400682

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC83046

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables exonuclease activity IEA
Inferred from Electronic Annotation
more info
 
enables poly(A)-specific ribonuclease activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within nuclear-transcribed mRNA poly(A) tail shortening IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in P-body IEA
Inferred from Electronic Annotation
more info
 
part_of PAN complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
poly(A) specific ribonuclease subunit PAN2 S homeolog
Names
PAN2 poly(A) specific ribonuclease subunit S homeolog
PAN2 poly(A) specific ribonuclease subunit homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092532.1NP_001086001.1  poly(A) specific ribonuclease subunit PAN2 S homeolog

    See identical proteins and their annotated locations for NP_001086001.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073679
    UniProtKB/TrEMBL
    Q6GN41
    Conserved Domains (3) summary
    cl02553
    Location:497581
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    sd00039
    Location:108156
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:158292
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    129664331..129679634
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)