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capn9.L calpain 9 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444426, updated on 4-Nov-2024

Summary

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Official Symbol
capn9.L
Official Full Name
calpain 9 L homeolog
Primary source
Xenbase:XB-GENE-948348
Locus tag
XELAEV_18026825mg
See related
EnsemblRapid:ENSXLAG00005029858 AllianceGenome:Xenbase:XB-GENE-948348
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
capn9
Summary
Predicted to enable calcium ion binding activity and calcium-dependent cysteine-type endopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human CAPN9 (calpain 9). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See capn9.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
20
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (54364138..54411406, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (53117995..53164028, complement)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene URB2 ribosome biogenesis 2 homolog L homeolog Neighboring gene TATA-box binding protein associated factor 5 like L homeolog Neighboring gene uncharacterized LOC121393669 Neighboring gene provisional ortholog of unc-93 homolog A L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC83034

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
calpain 9 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092528.1 → NP_001085997.1  calpain 9 L homeolog

    See identical proteins and their annotated locations for NP_001085997.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073673
    UniProtKB/TrEMBL
    Q6GN47
    Related
    ENSXLAP00005089395.1, ENSXLAT00005091065.1
    Conserved Domains (3) summary
    pfam00648
    Location:43 → 335
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:349 → 491
    Calpain_III; Calpain large subunit, domain III
    cl08302
    Location:569 → 616
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    54364138..54411406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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