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ascl1.S achaete-scute family bHLH transcription factor 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444423, updated on 4-Nov-2024

Summary

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Official Symbol
ascl1.S
Official Full Name
achaete-scute family bHLH transcription factor 1 S homeolog
Primary source
Xenbase:XB-GENE-17340658
Locus tag
XELAEV_18021297mg
See related
EnsemblRapid:ENSXLAG00005014744 AllianceGenome:Xenbase:XB-GENE-17340658
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ash1; Mash1; Xash1
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Predicted to act upstream of or within developmental process and regulation of transcription by RNA polymerase II. Orthologous to human ASCL1 (achaete-scute family bHLH transcription factor 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ascl1.S in Genome Data Viewer
Location:
chromosome: 3S
Exon count:
2
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3S NC_054376.1 (97599545..97602382)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3S NC_030729.1 (95729459..95732296)

Chromosome 3S - NC_054376.1Genomic Context describing neighboring genes Neighboring gene thymine DNA glycosylase S homeolog Neighboring gene phenylalanine hydroxylase S homeolog Neighboring gene uncharacterized LOC108713208 Neighboring gene 5'-nucleotidase domain containing 3 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC83023

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within developmental process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
achaete-scute family bHLH transcription factor 1 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092525.1 → NP_001085994.1  achaete-scute family bHLH transcription factor 1 S homeolog

    See identical proteins and their annotated locations for NP_001085994.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073667
    UniProtKB/TrEMBL
    Q6GN53
    Related
    ENSXLAP00005043159.1, ENSXLAT00005044227.1
    Conserved Domains (1) summary
    smart00353
    Location:89 → 131
    HLH; helix loop helix domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    97599545..97602382
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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