U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ikzf3.L IKAROS family zinc finger 3 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444381, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
ikzf3.L
Official Full Name
IKAROS family zinc finger 3 L homeolog
Primary source
Xenbase:XB-GENE-994463
Locus tag
XELAEV_18043158mg
See related
EnsemblRapid:ENSXLAG00005026895 AllianceGenome:Xenbase:XB-GENE-994463
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
aio; ikzf3; aiolos; znfn1a3
Summary
Predicted to enable DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and metal ion binding activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human IKZF3 (IKAROS family zinc finger 3). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ikzf3.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (2114299..2146266)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (2077991..2109990)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 3C L homeolog Neighboring gene zona pellucida binding protein 2 L homeolog Neighboring gene retinol dehydrogenase 8-like Neighboring gene growth factor receptor bound protein 7 L homeolog

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC82887

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
IKAROS family zinc finger 3 L homeolog
Names
IKAROS family zinc finger 3 (Aiolos)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092483.1 → NP_001085952.1  IKAROS family zinc finger 3 L homeolog

    See identical proteins and their annotated locations for NP_001085952.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073588
    UniProtKB/TrEMBL
    A0A974H240, Q6GNC6
    Related
    ENSXLAP00005079901.1, ENSXLAT00005081492.1
    Conserved Domains (3) summary
    COG5048
    Location:155 → 298
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:130 → 150
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:143 → 167
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    2114299..2146266
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041575635.1 → XP_041431569.1  IKAROS family zinc finger 3 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1LQN9, A0A974H240
    Conserved Domains (2) summary
    COG5048
    Location:154 → 297
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:129 → 149
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials