mEFTu1 mitochondrial translation elongation factor Tu 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mEFTu1provided by FlyBase
Official Full Name: mitochondrial translation elongation factor Tu 1provided by FlyBase
Primary source: FLYBASE:FBgn0024556
Locus tag: Dmel_CG6050
See related: AllianceGenome:FB:FBgn0024556
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG6050; Dmel\CG6050; dTUFm; EF-Tu1; eftu-M; efTuM; EfTuM; l(3)L4569; mtEF-Tu; TUFm
Summary: Predicted to enable GTPase activity and translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Located in mitochondrion. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 4. Orthologous to human TUFM (Tu translation elongation factor, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (13507557..13509332)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (9395062..9396837)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Drosophila melanogaster mitochondrial EF-Tu has two isoforms.
Title: Duplication of Drosophila melanogaster mitochondrial EF-Tu: pre-adaptation to T-arm truncation and exclusion of bulky aminoacyl residues.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables GTPase activity	ISS Inferred from Sequence or Structural Similarity more info
enables translation elongation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation elongation factor activity	IEA Inferred from Electronic Annotation more info
enables translation elongation factor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in mitochondrial translational elongation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translational elongation	IEA Inferred from Electronic Annotation more info
involved_in translational elongation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in mitochondrion	HDA more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

Names: CG6050-PA; CG6050-PB; elongation factor Tu mitochondrial; mEFTu1-PA; mEFTu1-PB; translation elongation factor Tu

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The following sections contain reference sequences that belong to a specific genome build. Explain