chmp4c.L charged multivesicular body protein 4C L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: chmp4c.L
Official Full Name: charged multivesicular body protein 4C L homeolog
Primary source: Xenbase:XB-GENE-954324
Locus tag: XELAEV_18032143mg
See related: EnsemblRapid:ENSXLAG00005028757 AllianceGenome:Xenbase:XB-GENE-954324
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: chmp4c
Summary: Predicted to act upstream of or within midbody abscission; mitotic cytokinesis checkpoint signaling; and negative regulation of cytokinesis. Predicted to be located in cytoplasmic side of plasma membrane; cytosol; and late endosome. Predicted to be part of ESCRT III complex. Orthologous to human CHMP4C (charged multivesicular body protein 4C). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 6L

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	6L	NC_054381.1 (133754732..133768966)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	6L	NC_030734.1 (124583308..124597530)

Chromosome 6L - NC_054381.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Process	Evidence Code	Pubs
acts_upstream_of_or_within late endosome to vacuole transport via multivesicular body sorting pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within midbody abscission	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within mitotic cytokinesis checkpoint signaling	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within negative regulation of cytokinesis	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vacuolar transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vesicle budding from membrane	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of ESCRT III complex	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic side of plasma membrane	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in late endosome membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in multivesicular body	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: charged multivesicular body protein 4c

Names: chromatin modifying protein 4C; chromatin-modifying protein 4c

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.