cttn.L cortactin L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: cttn.L
Official Full Name: cortactin L homeolog
Primary source: Xenbase:XB-GENE-492438
Locus tag: XELAEV_18021903mg
See related: AllianceGenome:Xenbase:XB-GENE-492438
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: cttn; ems1
Summary: Predicted to enable actin filament binding activity. Predicted to act upstream of or within regulation of actin filament polymerization. Predicted to be located in actin cytoskeleton; plasma membrane; and site of polarized growth. Orthologous to human CTTN (cortactin). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 4L

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4L	NC_054377.1 (10723343..10755970)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4L	NC_030730.1 (10185339..10217909)

Chromosome 4L - NC_054377.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables actin filament binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of actin filament polymerization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in actin filament	IEA Inferred from Electronic Annotation more info
located_in cortical actin cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in site of polarized growth	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cortactin L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001092402.1 → NP_001085871.1 cortactin L homeolog

See identical proteins and their annotated locations for NP_001085871.1

Status: PROVISIONAL

Source sequence(s)

BC073454

UniProtKB/TrEMBL

Q6GNQ0, Q8UWC3

Conserved Domains (2) summary

cd11959
Location:506 → 557

SH3_Cortactin; Src homology 3 domain of Cortactin

pfam02218
Location:192 → 227

HS1_rep; Repeat in HS1/Cortactin