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chrna1.2.L cholinergic receptor, nicotinic, alpha 1 (muscle), gene 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444296, updated on 17-Aug-2024

Summary

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Official Symbol
chrna1.2.L
Official Full Name
cholinergic receptor, nicotinic, alpha 1 (muscle), gene 2 L homeolog
Primary source
Xenbase:XB-GENE-5932081
Locus tag
XELAEV_18044719mg
See related
EnsemblRapid:ENSXLAG00005023483
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
chrna1.2
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Genomic context

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See chrna1.2.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (77388487..77397149, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (66877949..66886631, complement)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 155 L homeolog Neighboring gene WAS/WASL interacting protein family member 1 L homeolog Neighboring gene cholinergic receptor, nicotinic alpha 1 L homeolog Neighboring gene 35 kDa serum lectin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC80957

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables acetylcholine-gated monoatomic cation-selective channel activity IEA
Inferred from Electronic Annotation
more info
  
enables excitatory extracellular ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within nervous system process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
  
located_in synapse IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cholinergic receptor, nicotinic, alpha 1 (muscle), gene 2 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092400.1 → NP_001085869.1  cholinergic receptor, nicotinic, alpha 1 (muscle), gene 2 L homeolog precursor

    See identical proteins and their annotated locations for NP_001085869.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073452
    UniProtKB/TrEMBL
    A0A974BZK9, Q6GNQ2
    Related
    ENSXLAP00005069769.1, ENSXLAT00005071305.1
    Conserved Domains (3) summary
    TIGR00860
    Location:24 → 447
    LIC; Cation transporter family protein
    pfam02931
    Location:24 → 231
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:238 → 446
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    77388487..77397149 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials