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fes.S FES proto-oncogene, tyrosine kinase S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444292, updated on 3-Jul-2024

Summary

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Official Symbol
fes.S
Official Full Name
FES proto-oncogene, tyrosine kinase S homeolog
Primary source
Xenbase:XB-GENE-6067143
Locus tag
XELAEV_18020544mg
See related
EnsemblRapid:ENSXLAG00005013612
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
fes; fps; c-fes
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Genomic context

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See fes.S in Genome Data Viewer
Location:
chromosome: 3S
Exon count:
20
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3S NC_054376.1 (46368153..46420913, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3S NC_030729.1 (45092792..45145501, complement)

Chromosome 3S - NC_054376.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121402153 Neighboring gene mannosidase, alpha, class 2A, member 2 S homeolog Neighboring gene furin, paired basic amino acid cleaving enzyme S homeolog Neighboring gene 60S ribosomal protein L37a Neighboring gene microfibril associated protein 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC80946

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
FES proto-oncogene, tyrosine kinase S homeolog; tyrosine-protein kinase Fes/Fps

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    46368153..46420913 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041588254.1 → XP_041444188.1  tyrosine-protein kinase Fes/Fps

    UniProtKB/TrEMBL
    A0A8J1MS51, Q6GNQ8
    Related
    ENSXLAP00005040140.1, ENSXLAT00005041063.1
    Conserved Domains (3) summary
    cd07685
    Location:7 → 243
    F-BAR_Fes; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Fes (feline sarcoma) tyrosine kinase
    cd10361
    Location:453 → 537
    SH2_Fps_family; Src homology 2 (SH2) domain found in feline sarcoma, Fujinami poultry sarcoma, and fes-related (Fes/Fps/Fer) proteins
    cd05084
    Location:564 → 815
    PTKc_Fes; Catalytic domain of the Protein Tyrosine Kinase, Fes

  2. XM_041588255.1 → XP_041444189.1  tyrosine-protein kinase Fes/Fps

    UniProtKB/TrEMBL
    A0A8J1MS51, Q6GNQ8
    Conserved Domains (3) summary
    cd07685
    Location:7 → 243
    F-BAR_Fes; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Fes (feline sarcoma) tyrosine kinase
    cd10361
    Location:453 → 537
    SH2_Fps_family; Src homology 2 (SH2) domain found in feline sarcoma, Fujinami poultry sarcoma, and fes-related (Fes/Fps/Fer) proteins
    cd05084
    Location:564 → 815
    PTKc_Fes; Catalytic domain of the Protein Tyrosine Kinase, Fes

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001092396.1: Suppressed sequence

    Description
    NM_001092396.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

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