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tfg.L trafficking from ER to golgi regulator L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444288, updated on 4-Nov-2024

Summary

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Official Symbol
tfg.L
Official Full Name
trafficking from ER to golgi regulator L homeolog
Primary source
Xenbase:XB-GENE-6255684
Locus tag
XELAEV_18012872mg
See related
EnsemblRapid:ENSXLAG00005003136 AllianceGenome:Xenbase:XB-GENE-6255684
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tfga; xtfg; tfg-a; tfg-b
Summary
Predicted to enable identical protein binding activity. Predicted to act upstream of or within COPII vesicle coating. Predicted to be located in endoplasmic reticulum exit site. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 57. Orthologous to human TFG (trafficking from ER to golgi regulator). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tfg.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (109746973..109802683, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (103910403..103933273, complement)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene interphotoreceptor matrix proteoglycan 2 L homeolog Neighboring gene ABI family member 3 binding protein L homeolog Neighboring gene gem nuclear organelle associated protein 8 L homeolog Neighboring gene glycoprotein M6B L homeolog Neighboring gene oral-facial-digital syndrome 1 L homeolog Neighboring gene trafficking protein particle complex subunit 2 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within COPII vesicle coating IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum exit site IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
trk-fused a
Names
trk-fused gene L homeolog
trk-fused gene a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092392.1 → NP_001085861.1  trk-fused a

    See identical proteins and their annotated locations for NP_001085861.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073440
    UniProtKB/TrEMBL
    A0A974DR30, Q6GNR3
    Conserved Domains (2) summary
    cd06401
    Location:11 → 91
    PB1_TFG; The PB1 domain found in TFG protein, an oncogenic gene product and fusion partner to nerve growth factor tyrosine kinase receptor TrkA and to the tyrosine kinase ALK. The PB1 domain is a modular domain mediating specific protein-protein interaction in ...
    pfam17093
    Location:323 → 378
    PBP_N; Penicillin-binding protein N-terminus

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    109746973..109802683 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041580992.1 → XP_041436926.1  trk-fused a isoform X1

    UniProtKB/TrEMBL
    A0A1L8HGI0, A0A974DQC4, A0A974DR30
    Conserved Domains (2) summary
    cd06401
    Location:11 → 91
    PB1_TFG; The PB1 domain found in TFG protein, an oncogenic gene product and fusion partner to nerve growth factor tyrosine kinase receptor TrkA and to the tyrosine kinase ALK. The PB1 domain is a modular domain mediating specific protein-protein interaction in ...
    PHA03247
    Location:125 → 402
    PHA03247; large tegument protein UL36; Provisional

  2. XM_018245064.2 → XP_018100553.1  trk-fused a isoform X1

    UniProtKB/TrEMBL
    A0A1L8HGI0, A0A974DQC4, A0A974DR30
    Related
    ENSXLAP00005009317.1, ENSXLAT00005009458.1
    Conserved Domains (2) summary
    cd06401
    Location:11 → 91
    PB1_TFG; The PB1 domain found in TFG protein, an oncogenic gene product and fusion partner to nerve growth factor tyrosine kinase receptor TrkA and to the tyrosine kinase ALK. The PB1 domain is a modular domain mediating specific protein-protein interaction in ...
    PHA03247
    Location:125 → 402
    PHA03247; large tegument protein UL36; Provisional
Nucleotide Protein Strain
Heading Accession and Version

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