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ddost.S dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444283, updated on 4-Nov-2024

Summary

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Official Symbol
ddost.S
Official Full Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) S homeolog
Primary source
Xenbase:XB-GENE-5785164
Locus tag
XELAEV_18038011mg
See related
EnsemblRapid:ENSXLAG00005009752 AllianceGenome:Xenbase:XB-GENE-5785164
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ddost
Summary
Predicted to act upstream of or within protein glycosylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ir. Orthologous to human DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ddost.S in Genome Data Viewer
Location:
chromosome: 7S
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7S NC_054384.1 (110002836..110011790, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7S NC_030737.1 (87354514..87363468)

Chromosome 7S - NC_054384.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121396630 Neighboring gene neural cell adhesion molecule 1-like Neighboring gene ATPase H+/K+ transporting subunit alpha S homeolog Neighboring gene transmembrane protein 147 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nishiyama A, et al. Nat Commun, 2020 Mar 6. PMID 32144273, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC80921

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within protein N-linked glycosylation via asparagine IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein glycosylation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of oligosaccharyltransferase complex IEA
Inferred from Electronic Annotation
more info
  
part_of oligosaccharyltransferase complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Names
DDOST 48 kDa subunit
Oligosaccharyl transferase 48 kDa subunit
dolichyl-diphosphooligosaccharide-protein glycosyltransferase
NP_001085856.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092387.1 → NP_001085856.1  dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor

    See identical proteins and their annotated locations for NP_001085856.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073434
    UniProtKB/Swiss-Prot
    Q6GNR9
    UniProtKB/TrEMBL
    A0A974HAR7
    Related
    ENSXLAP00005028626.1, ENSXLAT00005029364.1
    Conserved Domains (1) summary
    pfam03345
    Location:30 → 437
    DDOST_48kD; Oligosaccharyltransferase 48 kDa subunit beta

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    110002836..110011790 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6GNR9.1 GenPept UniProtKB/Swiss-Prot:Q6GNR9

Gene LinkOut

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