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cldn5.S claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444247, updated on 4-Nov-2024

Summary

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Official Symbol
cldn5.S
Official Full Name
claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) S homeolog
Primary source
Xenbase:XB-GENE-17332561
Locus tag
XELAEV_18010542mg
See related
EnsemblRapid:ENSXLAG00005010920 AllianceGenome:Xenbase:XB-GENE-17332561
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
claudin-5
Summary
Predicted to enable structural molecule activity. Predicted to act upstream of or within bicellular tight junction assembly and cell adhesion. Predicted to be located in bicellular tight junction and plasma membrane. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CLDN5 (claudin 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cldn5.S in Genome Data Viewer
Location:
chromosome: 1S
Exon count:
1
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (143103408..143104467, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (127348467..127349526, complement)

Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene ubiquitin recognition factor in ER associated degradation 1 S homeolog Neighboring gene cell division cycle 45 S homeolog Neighboring gene septin 5 gene 2 S homeolog Neighboring gene septin 5 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC80834

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within bicellular tight junction assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092351.1 → NP_001085820.1  claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) S homeolog

    See identical proteins and their annotated locations for NP_001085820.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073390
    UniProtKB/TrEMBL
    A0A974I228, Q6GNW1
    Related
    ENSXLAP00005032180.1, ENSXLAT00005032964.1
    Conserved Domains (1) summary
    cl21598
    Location:5 → 170
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    143103408..143104467 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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