macroh2a2.S macroH2A.2 histone S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: macroh2a2.S
Official Full Name: macroH2A.2 histone S homeolog
Primary source: Xenbase:XB-GENE-17345810
Locus tag: XELAEV_18037160mg
See related: EnsemblRapid:ENSXLAG00005005003 AllianceGenome:Xenbase:XB-GENE-17345810
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: h2afy2
Summary: Predicted to enable chromatin DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to act upstream of or within nucleosome assembly. Predicted to be located in chromatin and nucleus. Predicted to be part of nucleosome. Orthologous to human MACROH2A2 (macroH2A.2 histone). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 7S

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7S	NC_054384.1 (34800269..34832639)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7S	NC_030737.1 (33202405..33234770)

Chromosome 7S - NC_054384.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables chromatin DNA binding	IEA Inferred from Electronic Annotation more info
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info
enables structural constituent of chromatin	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within chromatin organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nucleosome assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chromatin	IEA Inferred from Electronic Annotation more info
located_in chromosome	IEA Inferred from Electronic Annotation more info
part_of nucleosome	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: macroH2A.2 histone S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001092272.1 → NP_001085741.1 macroH2A.2 histone S homeolog

See identical proteins and their annotated locations for NP_001085741.1

Status: PROVISIONAL

Source sequence(s)

BC073272

UniProtKB/TrEMBL

A0A974CBQ3, Q6GP69

Related

ENSXLAP00005014945.1, ENSXLAT00005015143.1

Conserved Domains (2) summary

cd00074
Location:5 → 117

H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...

cd02904
Location:177 → 367

Macro_H2A-like; macrodomain, macroH2A-like family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

34800269..34832639

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041570481.1 → XP_041426415.1 macroH2A.2 histone S homeolog isoform X1

UniProtKB/TrEMBL

A0A974CBQ3, Q6GP69

Conserved Domains (2) summary

cd00074
Location:5 → 117

H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...

cd02904
Location:177 → 367

Macro_H2A-like; macrodomain, macroH2A-like family
XM_018226918.2 → XP_018082407.1 macroH2A.2 histone S homeolog isoform X1

UniProtKB/TrEMBL

A0A974CBQ3, Q6GP69

Related

ENSXLAP00005014935.1, ENSXLAT00005015133.1

Conserved Domains (2) summary

cd00074
Location:5 → 117

H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...

cd02904
Location:177 → 367

Macro_H2A-like; macrodomain, macroH2A-like family