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tyk2.L tyrosine kinase 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444089, updated on 18-Sep-2024

Summary

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Official Symbol
tyk2.L
Official Full Name
tyrosine kinase 2 L homeolog
Primary source
Xenbase:XB-GENE-993655
Locus tag
XELAEV_18019008mg
See related
EnsemblRapid:ENSXLAG00005001660
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tyk2
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Genomic context

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See tyk2.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
25
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (147056970..147102739, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (130764047..130810393, complement)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108711699 Neighboring gene ribonucleoprotein, PTB-binding 1 L homeolog Neighboring gene hsp90 co-chaperone Cdc37-like Neighboring gene uncharacterized LOC108710172

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC83617

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables growth hormone receptor binding IEA
Inferred from Electronic Annotation
more info
  
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tyrosine kinase 2 L homeolog
NP_001085663.1
XP_018106420.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092194.1 → NP_001085663.1  tyrosine kinase 2 L homeolog

    See identical proteins and their annotated locations for NP_001085663.1

    Status: PROVISIONAL

    Source sequence(s)
    BC073112
    UniProtKB/TrEMBL
    Q6GPK5
    Conserved Domains (7) summary
    smart00219
    Location:889 → 1161
    TyrKc; Tyrosine kinase, catalytic domain
    smart00295
    Location:25 → 277
    B41; Band 4.1 homologues
    cd05076
    Location:588 → 860
    PTK_Tyk2_rpt1; Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Tyrosine kinase 2
    cd05080
    Location:884 → 1166
    PTKc_Tyk2_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Tyrosine kinase 2
    cd13335
    Location:272 → 432
    FERM_C_TYK2; FERM domain C-lobe of Non-receptor tyrosine-protein kinase TYK2
    pfam07714
    Location:593 → 859
    Pkinase_Tyr; Protein tyrosine kinase
    cl15255
    Location:432 → 528
    SH2; Src homology 2 (SH2) domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    147056970..147102739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018250931.2 → XP_018106420.1  tyrosine kinase 2 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8H2U7, A0A974DGD7
    Related
    ENSXLAP00005004929.1, ENSXLAT00005005035.1
Nucleotide Protein Strain
Heading Accession and Version

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