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sh3bgr.L SH3 domain binding glutamate-rich protein L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444023, updated on 4-Nov-2024

Summary

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Official Symbol
sh3bgr.L
Official Full Name
SH3 domain binding glutamate-rich protein L homeolog
Primary source
Xenbase:XB-GENE-946025
Locus tag
XELAEV_18011431mg
See related
EnsemblRapid:ENSXLAG00005031578 AllianceGenome:Xenbase:XB-GENE-946025
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
sh3bgr; 21-garp
Summary
Predicted to be located in cytoplasm. Is expressed in anatomical system; pharyngeal arch; and primary germ layer. Orthologous to human SH3BGR (SH3 domain binding glutamate rich protein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sh3bgr.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (11015434..11048405, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (10785241..10818329, complement)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene beta-1,3-galactosyltransferase 5 gene 2 L homeolog Neighboring gene beta-1,3-galactosyltransferase 5 gene 1 L homeolog Neighboring gene guided entry of tail-anchored proteins factor 1 L homeolog Neighboring gene high mobility group nucleosome binding domain 1 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A thioredoxin fold protein Sh3bgr regulates Enah and is necessary for proper sarcomere formation. Jang DG, et al. Dev Biol, 2015 Sep 1. PMID 26116879, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Sh3bgr does its function at least partly by regulating localization of Enah for the sarcomere formation.
    Title: A thioredoxin fold protein Sh3bgr regulates Enah and is necessary for proper sarcomere formation.
Submit: New GeneRIF Correction

General gene information

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Homology

Clone Names

  • MGC82574

Gene Ontology Provided by Xenbase

Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
SH3 domain binding glutamate-rich protein L homeolog
Names
SH3 domain binding glutamic acid-rich protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092128.1 → NP_001085597.1  SH3 domain binding glutamate-rich protein L homeolog

    See identical proteins and their annotated locations for NP_001085597.1

    Status: PROVISIONAL

    Source sequence(s)
    BC072997
    UniProtKB/TrEMBL
    A0A974DKU5, Q6GPW0
    Related
    ENSXLAP00005094680.1, ENSXLAT00005096383.1
    Conserved Domains (2) summary
    cd03030
    Location:2 → 97
    GRX_SH3BGR; Glutaredoxin (GRX) family, SH3BGR (SH3 domain binding glutamic acid-rich protein) subfamily; a recently-identified subfamily composed of SH3BGR and similar proteins possessing significant sequence similarity to GRX, but without a redox active CXXC motif. ...
    cl23751
    Location:71 → 161
    Plasmodium_Vir; Plasmodium vivax Vir protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    11015434..11048405 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018245045.2 → XP_018100534.1  SH3 domain binding glutamate-rich protein L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A1L8HCB2, A0A974DLU8, Q66L08

  2. XM_018245044.2 → XP_018100533.1  SH3 domain binding glutamate-rich protein L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J0UAS9
    Related
    ENSXLAP00005094735.1, ENSXLAT00005096437.1

  3. XM_018245042.2 → XP_018100531.1  SH3 domain binding glutamate-rich protein L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J0U3U4
    Related
    ENSXLAP00005094810.1, ENSXLAT00005096514.1
Nucleotide Protein Strain
Heading Accession and Version

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