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prdx5.L peroxiredoxin 5 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 444006, updated on 4-Nov-2024

Summary

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Official Symbol
prdx5.L
Official Full Name
peroxiredoxin 5 L homeolog
Primary source
Xenbase:XB-GENE-1006737
Locus tag
XELAEV_18022201mg
See related
EnsemblRapid:ENSXLAG00005017966 AllianceGenome:Xenbase:XB-GENE-1006737
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
acr1; prx5; prxv; pmp20; prdx5; prx-5; sbbi10; aoeb166
Summary
Predicted to enable thioredoxin peroxidase activity. Predicted to act upstream of or within cell redox homeostasis; cellular response to oxidative stress; and hydrogen peroxide catabolic process. Predicted to be located in mitochondrion and peroxisomal matrix. Is expressed in anatomical system; pharyngeal arch; and primary germ layer. Orthologous to human PRDX5 (peroxiredoxin 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See prdx5.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (26052160..26061034, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (24527465..24536339, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene LRRN4 C-terminal-like protein Neighboring gene girdin Neighboring gene estrogen related receptor alpha L homeolog Neighboring gene potassium channel, two pore domain subfamily K, member 4 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression analysis of the peroxiredoxin gene family during early development in Xenopus laevis. Shafer ME, et al. Gene Expr Patterns, 2011 Dec. PMID 21920462
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC82521

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables peroxidase activity IEA
Inferred from Electronic Annotation
more info
  
enables thioredoxin peroxidase activity IEA
Inferred from Electronic Annotation
more info
  
enables thioredoxin-dependent peroxiredoxin activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cellular response to oxidative stress IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within hydrogen peroxide catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisomal matrix IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
peroxiredoxin 5 L homeolog
NP_001085580.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001092111.1 → NP_001085580.1  peroxiredoxin 5 L homeolog precursor

    See identical proteins and their annotated locations for NP_001085580.1

    Status: PROVISIONAL

    Source sequence(s)
    BC072972
    UniProtKB/TrEMBL
    A0A974HNH0, Q6GPY3
    Related
    ENSXLAP00005053027.1, ENSXLAT00005054199.1
    Conserved Domains (2) summary
    cd03013
    Location:32 → 187
    PRX5_like; Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5 ...
    pfam00578
    Location:32 → 168
    AhpC-TSA; AhpC/TSA family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    26052160..26061034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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