ca6.L carbonic anhydrase 6 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ca6.L
Official Full Name: carbonic anhydrase 6 L homeolog
Primary source: Xenbase:XB-GENE-866311
Locus tag: XELAEV_18035586mg
See related: EnsemblRapid:ENSXLAG00005016421 AllianceGenome:Xenbase:XB-GENE-866311
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ca6; car6; gustin
Summary: Predicted to enable carbonate dehydratase activity and zinc ion binding activity. Predicted to act upstream of or within one-carbon metabolic process. Predicted to be located in extracellular space. Orthologous to human CA6 (carbonic anhydrase 6). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 7L

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7L	NC_054383.1 (91987031..92005646)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7L	NC_030736.1 (83385228..83403843)

Chromosome 7L - NC_054383.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables carbonate dehydratase activity	IEA Inferred from Electronic Annotation more info
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within one-carbon metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in extracellular space	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: carbonic anhydrase 6 L homeolog

Names: carbonic anhydrase VI

NP_001085550.1

EC 4.2.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001092081.1 → NP_001085550.1 carbonic anhydrase 6 L homeolog precursor

See identical proteins and their annotated locations for NP_001085550.1

Status: PROVISIONAL

Source sequence(s)

BC072918

UniProtKB/TrEMBL

A0A974HC82, Q6GQ30

Related

ENSXLAP00005048359.1, ENSXLAT00005049474.1

Conserved Domains (2) summary

cd03125
Location:35 → 284

alpha_CA_VI; Carbonic anhydrase alpha, isozyme VI. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed ...

cl22861
Location:343 → 519

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...