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Rpp30 RNaseP protein p30 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44392, updated on 10-May-2024

Summary

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Official Symbol
Rpp30provided by FlyBase
Official Full Name
RNaseP protein p30provided by FlyBase
Primary source
FLYBASE:FBgn0283652
Locus tag
Dmel_CG11606
See related
AllianceGenome:FB:FBgn0283652
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
#19/1; CG11606; coconut; Dmel\CG11606; l(2)k01901; RNase P; Rpp1
Summary
Predicted to enable ribonuclease P RNA binding activity. Involved in tRNA processing. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Orthologous to human RPP30 (ribonuclease P/MRP subunit p30). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See Rpp30 in Genome Data Viewer
Location:
21B5-21B5; 2-0.5 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (251039..252373, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (251039..252373, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene kismet Neighboring gene mir-965 stem loop Neighboring gene long non-coding RNA:CR44218 Neighboring gene Dihydrouridine synthase 1 Neighboring gene long non-coding RNA:CR44219 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The effects of matrices of paired substitutions in mid-acceptor stem on Drosophila tRNA(His) structure and end-processing. Mohan A, et al. J Mol Biol, 2000 Nov 3. PMID 11054295
  2. Serotonin synchronises convergent extension of ectoderm with morphogenetic gastrulation movements in Drosophila. Colas JF, et al. Mech Dev, 1999 Sep. PMID 10495273
  3. Biogenesis of RNase P RNA from an intron requires co-assembly with cognate protein subunits. Palsule G, et al. Nucleic Acids Res, 2019 Sep 19. PMID 31287870, Free PMC Article
  4. tRNA processing defects induce replication stress and Chk2-dependent disruption of piRNA transcription. Molla-Herman A, et al. EMBO J, 2015 Dec 14. PMID 26471728, Free PMC Article
  5. Inventory and analysis of the protein subunits of the ribonucleases P and MRP provides further evidence of homology between the yeast and human enzymes. Rosenblad MA, et al. Nucleic Acids Res, 2006. PMID 16998185, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribonuclease P RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in tRNA 5'-leader removal ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in tRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of multimeric ribonuclease P complex ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of nucleolar ribonuclease P complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonuclease MRP complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
RNaseP protein p30
Names
CG11606-PA
CG11606-PB
Rpp30-PA
Rpp30-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    251039..252373 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272879.1 → NP_001259808.1  RNaseP protein p30, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259808.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VPM0
    Conserved Domains (1) summary
    pfam01876
    Location:8 → 226
    RNase_P_p30; RNase P subunit p30

  2. NM_080010.4 → NP_524749.1  RNaseP protein p30, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524749.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VPM0
    Related
    FBpp0077802
    Conserved Domains (1) summary
    pfam01876
    Location:8 → 226
    RNase_P_p30; RNase P subunit p30
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VPM0 Q9VPM0

Gene LinkOut

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