rpa2.L replication protein A2 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: rpa2.L
Official Full Name: replication protein A2 L homeolog
Primary source: Xenbase:XB-GENE-865703
Locus tag: XELAEV_18012050mg
See related: EnsemblRapid:ENSXLAG00005027968
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: rpa2; repa2; rpa32; rpa34; rpa2-a
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Genomic context

Location:: chromosome: 2L

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2L	NC_054373.1 (59158645..59167294, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2L	NC_030726.1 (56687881..56696555, complement)

Chromosome 2L - NC_054373.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables damaged DNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables single-stranded DNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA recombination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA replication	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA replication	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within DNA replication checkpoint signaling	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within base-excision repair	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within double-strand break repair via homologous recombination	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within mismatch repair	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within nucleotide-excision repair	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within protein localization to chromosome	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within telomere maintenance	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of DNA replication factor A complex	ISS Inferred from Sequence or Structural Similarity more info
located_in PML body	IEA Inferred from Electronic Annotation more info
located_in PML body	ISS Inferred from Sequence or Structural Similarity more info
part_of chromatin	IDA Inferred from Direct Assay more info	PubMed
located_in intracellular organelle	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: replication protein A 32 kDa subunit-A

Names: RF-A protein 2; RP-A p32; RP-A p34; Replication factor A protein 2; Replication protein A 32 kDa subunit-A; Replication protein A 34 kDa subunit; replication protein A2, 32kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001091924.1 → NP_001085393.1 replication protein A 32 kDa subunit-A

See identical proteins and their annotated locations for NP_001085393.1

Status: PROVISIONAL

Source sequence(s)

BC072101

UniProtKB/Swiss-Prot

Q6IP18

UniProtKB/TrEMBL

A0A974DM00

Related

ENSXLAP00005083752.1, ENSXLAT00005085390.1

Conserved Domains (3) summary

COG5235
Location:28 → 273

RFA2; Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit [DNA replication, recombination, and repair]

cd04478
Location:76 → 170

RPA2_DBD_D; RPA2_DBD_D: A subfamily of OB folds corresponding to the OB fold of the central ssDNA-binding domain (DBD)-D of human RPA2 (also called RPA32). RPA2 is a subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which appears ...

pfam08784
Location:169 → 268

RPA_C; Replication protein A C terminal

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

59158645..59167294 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)