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SLC11A1 solute carrier family 11 member 1 [ Ovis aries (sheep) ]

Gene ID: 443365, updated on 5-Mar-2024

Summary

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Gene symbol
SLC11A1
Gene description
solute carrier family 11 member 1
See related
EnsemblRapid:ENSOARG00020007179
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Also known as
NRAMP1
Orthologs
human mouse all
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Genomic context

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See SLC11A1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 2 NC_056055.1 (220400399..220411388)

Chromosome 2 - NC_056055.1Genomic Context describing neighboring genes Neighboring gene small ribosomal subunit protein eS27-like Neighboring gene ciliogenesis associated TTC17 interacting protein Neighboring gene CTD small phosphatase 1 Neighboring gene microRNA mir-26b Neighboring gene villin 1 Neighboring gene ubiquitin specific peptidase 37

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056055.1 Chromosome 2 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. cDNA cloning, structural organization, and expression of the sheep NRAMP1 gene. Bussmann V, et al. Mamm Genome, 1998 Dec. PMID 9880672
  2. Two polymorphic microsatellite markers close to the ovine NRAMP gene. Pitel F, et al. Anim Genet, 1996 Feb. PMID 8624043
  3. Cloning, sequencing and linkage mapping of the NRAMP1 gene of sheep and deer. Matthews GD, et al. Anim Genet, 1998 Feb. PMID 9682440
  4. Cloning, sequencing, and localization of an ovine fragment of the NRAMP gene, a candidate for the ITY/LSH/BCG gene. Pitel F, et al. Mamm Genome, 1994 Dec. PMID 7894181
  5. The macrophage expressed variant of the bovine lysozyme-encoding gene maps to chromosome 5q23. Brunner RM, et al. Mamm Genome, 1994 Dec. PMID 7894180

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cadmium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables manganese ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in metal ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
natural resistance-associated macrophage protein 1
Names
NRAMP 1
natural resistance associated macrophage protein
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009345.1 → NP_001009345.1  natural resistance-associated macrophage protein 1

    See identical proteins and their annotated locations for NP_001009345.1

    Status: PROVISIONAL

    Source sequence(s)
    U70255
    UniProtKB/TrEMBL
    A0A836D5T8, W5QE37
    Related
    ENSOARP00020009062.2, ENSOART00020011025.2
    Conserved Domains (2) summary
    TIGR01197
    Location:76 → 476
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
    pfam01566
    Location:98 → 483
    Nramp; Natural resistance-associated macrophage protein

RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056055.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    220400399..220411388
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012111085.4 → XP_011966475.1  natural resistance-associated macrophage protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A836D5T8, W5QE37
    Conserved Domains (2) summary
    TIGR01197
    Location:106 → 506
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
    pfam01566
    Location:128 → 513
    Nramp; Natural resistance-associated macrophage protein

  2. XM_012111094.4 → XP_011966484.1  natural resistance-associated macrophage protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A836D5T8, W5QE37
    Related
    ENSOARP00020055043.1, ENSOART00020061447.1
    Conserved Domains (2) summary
    TIGR01197
    Location:106 → 506
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
    pfam01566
    Location:128 → 513
    Nramp; Natural resistance-associated macrophage protein

  3. XM_042242644.1 → XP_042098578.1  natural resistance-associated macrophage protein 1 isoform X3

    UniProtKB/Swiss-Prot
    O19035, P49280, Q9TSE9
    Conserved Domains (1) summary
    TIGR01197
    Location:1 → 389
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P49280.2 GenPept UniProtKB/Swiss-Prot:P49280

Gene LinkOut

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