Lncbate10 brown adipose tissue enriched long noncoding RNA 10 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Lncbate10provided by MGI
Official Full Name: brown adipose tissue enriched long noncoding RNA 10provided by MGI
Primary source: MGI:MGI:3045386
See related: Ensembl:ENSMUSG00000118229 AllianceGenome:MGI:3045386
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: A530050N04Rik
Summary: Involved in cellular response to hormone stimulus. Acts upstream of or within several processes, including brown fat cell differentiation; cellular response to cAMP; and cellular response to cold. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 18 E1; 18

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	18	NC_000084.7 (61603296..61617678, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	18	NC_000084.6 (61470225..61484607, complement)

Chromosome 18 - NC_000084.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

governed by the cAMP-cAMP response element-binding protein axis and required for a full brown fat differentiation and white fat browning program; mechanistically, lncBATE10 can decoy Celf1 from Pgc1alpha, thereby protecting Pgc1alpha mRNA from repression by Celf1
Title: Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulators.

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within brown fat cell differentiation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within cellular response to cAMP	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within cellular response to cold	IDA Inferred from Direct Assay more info	PubMed
involved_in cellular response to hormone stimulus	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to muscle activity	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.