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Ccin calicin [ Mus musculus (house mouse) ]

Gene ID: 442829, updated on 18-Sep-2024

Summary

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Official Symbol
Ccinprovided by MGI
Official Full Name
calicinprovided by MGI
Primary source
MGI:MGI:3045316
See related
Ensembl:ENSMUSG00000070999 AllianceGenome:MGI:3045316
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933417A14Rik
Summary
Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization and brain development. Predicted to act upstream of or within cell differentiation and spermatogenesis. Predicted to be located in cytoskeleton. Predicted to be active in actin cytoskeleton and dendrite cytoplasm. Orthologous to human CCIN (calicin). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human all
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Genomic context

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See Ccin in Genome Data Viewer
Location:
4 B1; 4 23.08 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (43983504..43985533)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (43983504..43985533)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene reversion-inducing-cysteine-rich protein with kazal motifs Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:43970150-43970259 Neighboring gene STARR-positive B cell enhancer ABC_E7964 Neighboring gene predicted gene, 30377 Neighboring gene STARR-positive B cell enhancer ABC_E1275 Neighboring gene STARR-seq mESC enhancer starr_10063 Neighboring gene GLI pathogenesis-related 2 Neighboring gene STARR-positive B cell enhancer ABC_E6167 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:44025298-44025528 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:44035322-44035529 Neighboring gene clathrin light chain A Neighboring gene glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Neighboring gene STARR-seq mESC enhancer starr_10067 Neighboring gene STARR-positive B cell enhancer ABC_E7965

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The perinuclear theca protein Calicin helps shape the sperm head and maintain the nuclear structure in mice. Zhang XZ, et al. Cell Rep, 2022 Jul 5. PMID 35793634
  2. Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Sang L, et al. Cell, 2011 May 13. PMID 21565611, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ubiquitin-like ligase-substrate adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Cul3-RING ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoskeletal calyx IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoskeleton ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
calicin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002787.2 → NP_001002787.1  calicin

    See identical proteins and their annotated locations for NP_001002787.1

    Status: PROVISIONAL

    Source sequence(s)
    AK030197
    Consensus CDS
    CCDS18118.1
    UniProtKB/Swiss-Prot
    Q8CDE2
    UniProtKB/TrEMBL
    B2RX51
    Related
    ENSMUSP00000092725.2, ENSMUST00000095107.3
    Conserved Domains (4) summary
    PHA03098
    Location:41 → 462
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:317 → 362
    Kelch; KELCH repeat [structural motif]
    cd18307
    Location:27 → 123
    BTB_POZ_calicin; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in calicin
    cl28903
    Location:130 → 208
    BACK; BACK (BTB and C-terminal Kelch) domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    43983504..43985533
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CDE2.1 GenPept UniProtKB/Swiss-Prot:Q8CDE2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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