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sns - sticks and stones

Enables cell adhesion mediator activity. Involved in several processes, including garland nephrocyte differentiation; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and sensory organ development. Located in nephrocyte diaphragm and plasma membrane. Is active in apical plasma membrane. Is expressed in several structures, including mesoderm; muscle system; nephrocyte; reproductive system; and retina. Used to study kidney disease and nephrotic syndrome type 1. Human ortholog(s) of this gene implicated in nephrotic syndrome type 1. Orthologous to human NPHS1 (NPHS1 adhesion molecule, nephrin). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa