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Ugt36A1 UDP-glycosyltransferase family 36 member A1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44058, updated on 18-Sep-2024

Summary

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Official Symbol
Ugt36A1provided by FlyBase
Official Full Name
UDP-glycosyltransferase family 36 member A1provided by FlyBase
Primary source
FLYBASE:FBgn0015663
Locus tag
Dmel_CG2788
See related
AllianceGenome:FB:FBgn0015663
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2788; Dmel\CG2788; Dot; UGT36A1
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in Pdf neuron of abdominal neuromere; adult head; circulatory system; and embryonic/larval gut. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to several human genes including UGT2A2 (UDP glucuronosyltransferase family 2 member A2); UGT2A3 (UDP glucuronosyltransferase family 2 member A3); and UGT2B10 (UDP glucuronosyltransferase family 2 member B10). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See Ugt36A1 in Genome Data Viewer
Location:
24A1-24A2; 2-10 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3619097..3621573)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3619097..3621573)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44310 Neighboring gene odd skipped Neighboring gene uncharacterized protein Neighboring gene foraging Neighboring gene mir-4972 stem loop Neighboring gene Dorsal root ganglia homeobox Neighboring gene Seminal fluid protein 24Ba

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila cellular immune system: Dorothy encodes a UDP glycosyltransferase. Zhou Z, et al. Adv Exp Med Biol, 2001. PMID 11418991
  2. The Dorothy enhancer has Tinman binding sites and drives hopscotch-induced tumor formation. Kimbrell DA, et al. Genesis, 2002 Sep-Oct. PMID 12324942
  3. Drosophila melanogaster and its nephrocytes: A versatile model for glomerular research. Odenthal J, et al. Methods Cell Biol, 2019. PMID 31493819
  4. SPARC-Dependent Cardiomyopathy in Drosophila. Hartley PS, et al. Circ Cardiovasc Genet, 2016 Apr. PMID 26839388, Free PMC Article
  5. Powerful, efficient QTL mapping in Drosophila melanogaster using bulked phenotyping and pooled sequencing. Macdonald SJ, et al. Genetics, 2022 Mar 3. PMID 35100395, Free PMC Article

See all (52) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables UDP-glycosyltransferase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycosylation ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
UDP-glycosyltransferase family 36 member A1
Names
CG2788-PA
CG2788-PB
Ugt36A1-PA
Ugt36A1-PB
dorothy

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    3619097..3621573
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298662.1 → NP_001285591.1  UDP-glycosyltransferase family 36 member A1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285591.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0IGZ3, Q9NBD8, Q9VQT0
    Conserved Domains (2) summary
    PHA03392
    Location:8 → 475
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:38 → 501
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

  2. NM_079947.5 → NP_524686.3  UDP-glycosyltransferase family 36 member A1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524686.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0IGZ3, Q9NBD8, Q9VQT0
    Conserved Domains (2) summary
    PHA03392
    Location:8 → 475
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:38 → 501
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7JVK2 Q7JVK2
Q9NBD8 Q9NBD8
Q9VQT0 Q9VQT0

Gene LinkOut

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