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Arf4 ADP ribosylation factor 4 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43823, updated on 18-Sep-2024

Summary

Official Symbol
Arf4provided by FlyBase
Official Full Name
ADP ribosylation factor 4provided by FlyBase
Primary source
FLYBASE:FBgn0013749
Locus tag
Dmel_CG11027
See related
AllianceGenome:FB:FBgn0013749
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Arf102E; arf102F; Arf102F; Arf2; ARF2; arf4; Arf5; ARFII; CG1102; CG11027; dARFII; Dmel\CG11027; P40945
Summary
Enables enzyme activator activity. Involved in compound eye development and protein ADP-ribosylation. Predicted to be active in cytoplasm and plasma membrane. Is expressed in adult head; adult heart; and organism. Orthologous to several human genes including ARF5 (ADP ribosylation factor 5). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Arf4 in Genome Data Viewer
Location:
102F8-102F8; 4-0 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 4 NC_004353.4 (1124167..1125325)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 4 NC_004353.3 (1144793..1145951)

Chromosome 4 - NC_004353.4Genomic Context describing neighboring genes Neighboring gene Activin-beta Neighboring gene shaven Neighboring gene Calsyntenin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Kinesin family member 3C

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables enzyme activator activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in compound eye development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in symbiont entry into host cell HMP PubMed 
involved_in synaptic vesicle endocytosis TAS
Traceable Author Statement
more info
PubMed 
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ADP ribosylation factor 4
Names
ADP ribosylation factor 102F
ADP ribosylation factor II
ADP ribosylation factor at 102F
Arf4-PA
Arf4-PB
CG11027-PA
CG11027-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004353.4 Reference assembly

    Range
    1124167..1125325
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079892.3NP_524631.1  ADP ribosylation factor 4, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524631.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P40945, Q9V499
    UniProtKB/TrEMBL
    L0MNA8
    Related
    FBpp0088256
    Conserved Domains (1) summary
    cl40481
    Location:1180
    YlqF_related_GTPase; Circularly permuted YlqF-related GTPases
  2. NM_001272158.1NP_001259087.1  ADP ribosylation factor 4, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259087.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P40945, Q9V499
    UniProtKB/TrEMBL
    L0MNA8
    Conserved Domains (1) summary
    cl40481
    Location:1180
    YlqF_related_GTPase; Circularly permuted YlqF-related GTPases