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lobo lost boys [ Drosophila melanogaster (fruit fly) ]

Gene ID: 4379864, updated on 18-Sep-2024

Summary

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Official Symbol
loboprovided by FlyBase
Official Full Name
lost boysprovided by FlyBase
Primary source
FLYBASE:FBgn0083946
Locus tag
Dmel_CG34110
See related
AllianceGenome:FB:FBgn0083946
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13661; CG13662; CG34110; Dmel\CG34110
Summary
Involved in flagellated sperm motility and sperm storage. Located in motile cilium. Is expressed in chordotonal neurons and spermatogonium. Orthologous to human DRC7 (dynein regulatory complex subunit 7). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See lobo in Genome Data Viewer
Location:
96C2-96C4; 3-87 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25169565..25193776, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20995287..21019498, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46474 Neighboring gene distal antenna-related Neighboring gene distal antenna Neighboring gene uncharacterized protein Neighboring gene Cadherin 96Ca Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila sperm motility in the reproductive tract. Yang Y, et al. Biol Reprod, 2011 May. PMID 21293028, Free PMC Article
  2. Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50. Yang Y, et al. Mol Biol Cell, 2011 Apr. PMID 21289096, Free PMC Article
  3. A Dnmt2-like protein mediates DNA methylation in Drosophila. Kunert N, et al. Development, 2003 Nov. PMID 12944428
  4. Distal antenna and distal antenna related encode nuclear proteins containing pipsqueak motifs involved in antenna development in Drosophila. Emerald BS, et al. Development, 2003 Mar. PMID 12571108
  5. The pipsqueak-domain proteins Distal antenna and Distal antenna-related restrict Hunchback neuroblast expression and early-born neuronal identity. Kohwi M, et al. Development, 2011 May. PMID 21429984, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in flagellated sperm motility IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in flagellated sperm motility IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sperm storage IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in motile cilium IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in motile cilium IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
lost boys
Names
CG34110-PC
lobo-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    25169565..25193776 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001043292.2 → NP_001036757.1  lost boys [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036757.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q4V516
    Conserved Domains (1) summary
    pfam01841
    Location:154 → 228
    Transglut_core; Transglutaminase-like superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4V516.1 Q4V516

Gene LinkOut

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