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psmf1 proteasome inhibitor subunit 1 [ Danio rerio (zebrafish) ]

Gene ID: 436820, updated on 2-Nov-2024

Summary

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Official Symbol
psmf1provided by ZNC
Official Full Name
proteasome inhibitor subunit 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-282
See related
Ensembl:ENSDARG00000022652 AllianceGenome:ZFIN:ZDB-GENE-040718-282
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92785
Summary
Predicted to enable endopeptidase inhibitor activity and proteasome binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be part of proteasome complex. Orthologous to human PSMF1 (proteasome inhibitor subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See psmf1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (51796296..51811173, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (51796297..51811174, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 74B Neighboring gene bladder cancer associated protein Neighboring gene R-spondin 4 Neighboring gene angiopoietin 4 Neighboring gene uncharacterized LOC137496026

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Xiao A, et al. Nucleic Acids Res, 2013 Aug. PMID 23748566, Free PMC Article
  2. RNA-seq liver transcriptome analysis reveals an activated MHC-I pathway and an inhibited MHC-II pathway at the early stage of vaccine immunization in zebrafish. Yang D, et al. BMC Genomics, 2012 Jul 17. PMID 22805612, Free PMC Article
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables proteasome binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
part_of proteasome complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
proteasome inhibitor PI31 subunit
Names
proteasome (prosome, macropain) inhibitor subunit 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002547.2 → NP_001002547.2  proteasome inhibitor PI31 subunit

    Status: VALIDATED

    Source sequence(s)
    BX001037, CD604800, EH484771
    UniProtKB/TrEMBL
    A0A0R4II16, A0A8M1N0P9
    Related
    ENSDARP00000133267.1, ENSDART00000161048.3
    Conserved Domains (2) summary
    pfam08577
    Location:186 → 249
    PI31_Prot_C; PI31 proteasome regulator
    pfam11566
    Location:11 → 139
    PI31_Prot_N; PI31 proteasome regulator N-terminal

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    51796296..51811173 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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