nubpl nucleotide binding protein-like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nubplprovided by ZNC
Official Full Name: nucleotide binding protein-likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-140
See related: Ensembl:ENSDARG00000054821 AllianceGenome:ZFIN:ZDB-GENE-040718-140
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92633
Summary: Predicted to enable 4 iron, 4 sulfur cluster binding activity. Predicted to be involved in iron-sulfur cluster assembly and mitochondrial respiratory chain complex I assembly. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 21. Orthologous to human NUBPL (NUBP iron-sulfur cluster assembly factor, mitochondrial). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (31719046..31726868)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (31702083..31709905)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 4 iron, 4 sulfur cluster binding	IBA Inferred from Biological aspect of Ancestor more info
enables 4 iron, 4 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP-dependent FeS chaperone activity	IEA Inferred from Electronic Annotation more info
enables iron-sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in iron-sulfur cluster assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within iron-sulfur cluster assembly	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial respiratory chain complex I assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: iron-sulfur cluster transfer protein NUBPL

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002442.1 → NP_001002442.1 iron-sulfur cluster transfer protein NUBPL

See identical proteins and their annotated locations for NP_001002442.1

Status: PROVISIONAL

Source sequence(s)

BC076121

UniProtKB/TrEMBL

A0A8M1N0J4, Q6DH61

Related

ENSDARP00000071545.4, ENSDART00000077077.5

Conserved Domains (2) summary

TIGR01969
Location:77 → 319

minD_arch; cell division ATPase MinD, archaeal

pfam10609
Location:73 → 319

ParA; NUBPL iron-transfer P-loop NTPase