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Tpi - Triose phosphate isomerase

Enables protein homodimerization activity and triose-phosphate isomerase activity. Involved in several processes, including determination of adult lifespan; glucose homeostasis; and glycolytic process. Located in M band and Z disc. Is expressed in several structures, including adult head; adult heart; muscle system; spermatozoon; and wing disc. Used to study neurodegenerative disease and triosephosphate isomerase deficiency. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder and triosephosphate isomerase deficiency. Orthologous to human TPI1 (triosephosphate isomerase 1). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa