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Slc2a7 solute carrier family 2 (facilitated glucose transporter), member 7 [ Mus musculus (house mouse) ]

Gene ID: 435818, updated on 28-Oct-2024

Summary

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Official Symbol
Slc2a7provided by MGI
Official Full Name
solute carrier family 2 (facilitated glucose transporter), member 7provided by MGI
Primary source
MGI:MGI:3650865
See related
Ensembl:ENSMUSG00000062064 AllianceGenome:MGI:3650865
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GLUT-7
Summary
Predicted to enable D-glucose transmembrane transporter activity and fructose transmembrane transporter activity. Predicted to be involved in D-glucose transmembrane transport and fructose transmembrane transport. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. Orthologous to human SLC2A7 (solute carrier family 2 member 7). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in duodenum adult (RPKM 33.3), small intestine adult (RPKM 16.9) and 1 other tissue See more
Orthologs
human all
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Genomic context

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See Slc2a7 in Genome Data Viewer
Location:
4 E2; 4 81.04 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (150233293..150253499)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (150148834..150169042)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 157 Neighboring gene STARR-seq mESC enhancer starr_12136 Neighboring gene solute carrier family 2 (facilitated glucose transporter), member 5 Neighboring gene STARR-positive B cell enhancer mm9_chr4:149512225-149512526 Neighboring gene predicted gene, 52492 Neighboring gene carbonic anhydrase 6 Neighboring gene STARR-seq mESC enhancer starr_12144 Neighboring gene STARR-positive B cell enhancer ABC_E8035 Neighboring gene enolase 1, alpha non-neuron

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables D-glucose transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
NOT enables D-glucose transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables fructose transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
NOT enables fructose transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables hexose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in D-glucose transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
NOT involved_in D-glucose transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in fructose transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
NOT involved_in fructose transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in monosaccharide transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
solute carrier family 2, facilitated glucose transporter member 7
Names
glucose transporter type 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085529.2 → NP_001078998.1  solute carrier family 2, facilitated glucose transporter member 7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL606971
    Consensus CDS
    CCDS51385.1
    UniProtKB/Swiss-Prot
    P0C6A1
    UniProtKB/TrEMBL
    B1ARZ3
    Related
    ENSMUSP00000059106.8, ENSMUST00000059893.8
    Conserved Domains (2) summary
    cd06174
    Location:93 → 479
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:27 → 494
    Sugar_tr; Sugar (and other) transporter

  2. NM_001368869.1 → NP_001355798.1  solute carrier family 2, facilitated glucose transporter member 7 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL606971
    UniProtKB/Swiss-Prot
    P0C6A1
    Conserved Domains (1) summary
    cd17432
    Location:26 → 478
    MFS_GLUT_Class2; Class 2 Glucose transporters (GLUTs) of the Major Facilitator Superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    150233293..150253499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320304.2 → XP_017175793.1  solute carrier family 2, facilitated glucose transporter member 7 isoform X1

    UniProtKB/Swiss-Prot
    P0C6A1
    Conserved Domains (1) summary
    cd17432
    Location:89 → 518
    MFS_GLUT_Class2; Class 2 Glucose transporters (GLUTs) of the Major Facilitator Superfamily

  2. XM_030253649.2 → XP_030109509.1  solute carrier family 2, facilitated glucose transporter member 7 isoform X3

    UniProtKB/Swiss-Prot
    P0C6A1
    Conserved Domains (1) summary
    cd17432
    Location:1 → 429
    MFS_GLUT_Class2; Class 2 Glucose transporters (GLUTs) of the Major Facilitator Superfamily

  3. XM_030253648.2 → XP_030109508.1  solute carrier family 2, facilitated glucose transporter member 7 isoform X2

    Conserved Domains (1) summary
    cl28910
    Location:87 → 419
    MFS; Major Facilitator Superfamily

  4. XM_030253650.2 → XP_030109510.1  solute carrier family 2, facilitated glucose transporter member 7 isoform X4

    Conserved Domains (1) summary
    cl28910
    Location:1 → 325
    MFS; Major Facilitator Superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0C6A1.1 GenPept UniProtKB/Swiss-Prot:P0C6A1

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